Disodium malonate

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Names

[ CAS No. ]:
141-95-7

[ Name ]:
Disodium malonate

[Synonym ]:
Malonic acid disodium salt monohydrate
MFCD00002708
Malonic acid, disodium salt
Disodium malonate
sodium malonate
EINECS 205-514-0
disodium propanedioate
MALONIC ACID DISODIUM SALT
1,3-Propanedioic acid disodium salt
Propanedioic acid, sodium salt (1:2)

Chemical & Physical Properties

[ Density]:
1.546g/cm3

[ Boiling Point ]:
386.8ºC at 760mmHg

[ Molecular Formula ]:
C3H2Na2O4

[ Molecular Weight ]:
148.025

[ Flash Point ]:
201.9ºC

[ Exact Mass ]:
147.974854

[ PSA ]:
80.26000

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OO1750000
CHEMICAL NAME :
Malonic acid, sodium salt
CAS REGISTRY NUMBER :
141-95-7
LAST UPDATED :
199712
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C3-H2-O4.2Na
MOLECULAR WEIGHT :
148.03
WISWESSER LINE NOTATION :
QV1VQ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 17,814,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1550 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 79,461,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 79,461,1949
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1584 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Endocrine - hyperglycemia
REFERENCE :
JBCHA3 Journal of Biological Chemistry. (428 E. Preston St., Baltimore, MD 21202) V.1- 1905- Volume(issue)/page/year: 161,55,1945
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 79,461,1949

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
OO1750000

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Malonic acid

DownStream

  • Benzoic anhydride
  • benzoic acid
  • Sodium ethoxide
  • Diethyl malonate
  • Dimethyl malonate
  • Propanedioic acid,1,3-bis(phenylmethyl) ester
  • DIALLYL MALONATE
  • Titanium, bis(h5-2,4-cyclopentadien-1-yl)[propanedioato(2-)-O,O']-(9CI)
  • Succinic acid
  • Oxalic acid

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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