N,N'-Bis(2-bromoethyl)phosphorodiamidic acid

Suppliers

Names

[ CAS No. ]:
141025-16-3

[ Name ]:
N,N'-Bis(2-bromoethyl)phosphorodiamidic acid

[Synonym ]:
N,N'-Bis(2-bromoethyl)phosphoric acid diamide
Phosphorodiamidic acid,N,N'-bis(2-bromoethyl)
HO-P(=O)(NHCH2CH2Br)2
bromoifosfamide mustard
Dibromo isophoramide mustard
N,N'-Bis(2-bromoethyl)phosphorodiamidic acid

Chemical & Physical Properties

[ Density]:
1.934g/cm3

[ Boiling Point ]:
370.2ºC at 760mmHg

[ Molecular Formula ]:
C4H11Br2N2O2P

[ Molecular Weight ]:
309.92400

[ Flash Point ]:
177.7ºC

[ Exact Mass ]:
307.89200

[ PSA ]:
71.17000

[ LogP ]:
1.83760

[ Vapour Pressure ]:
1.69E-06mmHg at 25°C

[ Index of Refraction ]:
1.557

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TD2516500
CHEMICAL NAME :
Phosphorodiamidic acid, N,N'-bis(2-bromoethyl)-
CAS REGISTRY NUMBER :
141025-16-3
LAST UPDATED :
199212
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H11-Br2-N2-O2-P
MOLECULAR WEIGHT :
309.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
800 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 43,937,1992

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Bromoethylamine hydrobromide

DownStream

Related Compounds

  • TH-302
  • N,N'-bis-(2-chloro-ethyl)-N-ethyl-phosphorodiamidic acid but-3-enyl ester
  • bis(2-hydroxyethylamino)phosphinic acid
  • 1,4-Cyclohexanedicarboxamide,N,N'-bis(2-chloroethyl)-, trans- (8CI)
  • Palifosfamide
  • O-(but-3-enyl) N,N'-bis(2-chloroethyl)phosphorodiamidate
  • 4-(3-Methylpyridin-4-yl)-1,3-oxazolidin-2-one
  • 2-(3-Bromo-2-hydroxyphenyl)-2-methylpropanal
  • 3-(2-Chloro-6-methylpyridin-3-yl)azetidin-3-ol
  • 1-(1-{[(Tert-butoxy)carbonyl]amino}cyclobutyl)-4-oxocyclohexane-1-carboxylic acid
  • 4-(2-{[(Prop-2-en-1-yloxy)carbonyl]amino}ethoxy)butanoic acid
  • 2-{4-[(Prop-2-en-1-yloxy)carbonyl]piperazin-1-yl}pyrimidine-5-carboxylic acid
  • 2-Chlorobicyclo[2.2.2]octane-2-carboxylic acid
  • 5-methyl-1-{1-[(prop-2-en-1-yloxy)carbonyl]piperidin-4-yl}-1H-1,2,3-triazole-4-carboxylic acid
  • (4-Chlorothiophen-2-yl)methanesulfonyl fluoride
  • 2-[(3-Hydroxyazetidin-3-yl)methyl]benzene-1,3,5-triol
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.