Cytochalasin A

Suppliers

Names

[ Name ]:
Cytochalasin A

[Synonym ]:
cytochalasin a from helminthosporium dematioideum
(3E,11Z)-16-Benzyl-13-hydroxy-9,15-diméthyl-14-méthylène-6,7,8,9,10,12a,13,14,15,15a,16,17-dodécahydro-2H-oxacyclotétradécino[2,3-d]isoindole-2,5,18-trione
MFCD00005935
20-dehydro-phomin
2H-Oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,11Z)-
(3E,11Z)-16-Benzyl-13-hydroxy-9,15-dimethyl-14-methylene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
7(S)-Hydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E),21(E)-triene-1,20,23-trione
CytochalasinA from Drechslera dematioidea
Cytochalasin A
(3E,11Z)-16-benzyl-13-hydroxy-9,15-dimethyl-14-methylidene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione
Dehydrophomin
EINECS 237-964-9
Cytochalasin dreschslera dematioidea
(3E,11Z)-16-Benzyl-13-hydroxy-9,15-dimethyl-14-methylen-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-oxacyclotetradecino[2,3-d]isoindol-2,5,18-trion
5,5-Didehydrophomin

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
725.1±60.0 °C at 760 mmHg

[ Melting Point ]:
147 to 148'ºC

[ Molecular Formula ]:
C₂₉H₃₅NO₅

[ Molecular Weight ]:
477.592

[ Flash Point ]:
392.3±32.9 °C

[ Exact Mass ]:
477.251526

[ PSA ]:
92.70000

[ LogP ]:
2.83

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
−20°C

[ Water Solubility ]:
ethanol: 20 mg/mL, clear, colorless | Soluble in DMF, DMSO, ethanol and acetone. Insoluble in water.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H310-H330-H361

[ Precautionary Statements ]:
P260-P264-P280-P284-P302 + P350-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+: Very toxic;T: Toxic;

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
28-36/37-45

[ RIDADR ]:
UN 1544 6.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Apical growth and mitosis are independent processes in Aspergillus nidulans.

Protoplasma 222(3-4) , 211-5, (2003)

It is well established that cytoplasmic microtubules are depolymerized during nuclear division and reassembled as mitotic microtubules. Mounting evidence showing that cytoplasmic microtubules were als...

Roles of the actin cytoskeleton and an actin-binding protein in wheat resistance against Puccinia striiformis f. sp. tritici.

Protoplasma 249(1) , 99-106, (2012)

Elucidating resistance mechanisms of plant cells against pathogens is essential to develop novel strategies of disease control. The actin cytoskeleton was found intimately involved in plant defense. I...

Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress.

J. Biol. Chem. 282(14) , 10370-9, (2007)

The results presented here demonstrate that focal adhesion kinase (FAK) Tyr-861 is the predominant tyrosine phosphorylation site stimulated by hyperosmotic stress in a variety of cell types, including...