1-hydroxy-2-[4-(trifluoromethyl)phenyl]indole-3-carbonitrile

Names

[ CAS No. ]:
141135-81-1

[ Name ]:
1-hydroxy-2-[4-(trifluoromethyl)phenyl]indole-3-carbonitrile

[Synonym ]:
1-Hydroxy-3-cyano-2-(4-trifluoromethylphenyl)indole
1H-Indole-3-carbonitrile,1-hydroxy-2-[4-(trifluoromethyl)phenyl]

Chemical & Physical Properties

[ Molecular Formula ]:
C16H9F3N2O

[ Molecular Weight ]:
302.25100

[ Exact Mass ]:
302.06700

[ PSA ]:
48.95000

[ LogP ]:
4.43608

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2-cyano-2-(2-nitrophenyl)acetate
  • Benzyl bromide
  • sodium carbonate
  • 1-(Bromomethyl)-4-(trifluoromethyl)benzene
  • Tetramethylguanidine

DownStream

Related Compounds

  • ethyl 2-(2-(2-((1-methyl-5-phenyl-1H-imidazol-2-yl)thio)acetamido)thiazol-4-yl)acetate
  • ethyl 2-(2-((5-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-yl)thio)acetamido)-4-methylthiazole-5-carboxylate
  • 2,4-dichloro-N-(4-{2-methyl-4-oxo-3H,4H-pyrido[2,3-d]pyrimidin-3-yl}phenyl)benzamide
  • 2,5-dichloro-N-(4-(2-methyl-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)phenyl)benzamide
  • 2,4-dichloro-N-(2-methyl-4-(2-methyl-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl)phenyl)benzamide
  • N-(4-acetamidophenyl)-2-[2-(5-methyl-1,3,4-oxadiazol-2-yl)-1H-indol-1-yl]acetamide
  • 2-(3-benzyl-2,4-dioxo-3,4-dihydropyrido[3,2-d]pyrimidin-1(2H)-yl)-N-(2,4-dimethoxyphenyl)acetamide
  • 2-(3-benzyl-2,4-dioxo-3,4-dihydropyrido[3,2-d]pyrimidin-1(2H)-yl)-N-(2,5-dimethoxyphenyl)acetamide
  • 2-(3-(4-methoxybenzyl)-2,4-dioxo-3,4-dihydropyrido[3,2-d]pyrimidin-1(2H)-yl)-N-(2-methoxyphenyl)acetamide
  • 2-(3-(4-methoxybenzyl)-2,4-dioxo-3,4-dihydropyrido[3,2-d]pyrimidin-1(2H)-yl)-N-(3-methoxyphenyl)acetamide
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