PEPA

Names

[ Name ]:
PEPA

[Synonym ]:
2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide
2-[4-[2-(benzenesulfonamido)ethylsulfanyl]-2,6-difluorophenoxy]acetamide
PEPA

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₆F₂N₂O₄S₂

[ Molecular Weight ]:
402.43600

[ Exact Mass ]:
402.05200

[ PSA ]:
132.17000

[ LogP ]:
4.07150

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Positive modulation of AMPA receptors prevents downregulation of GluR2 expression and activates the Lyn-ERK1/2-CREB signaling in rat brain ischemia.

Psychopharmacology 20 , 65-77, (2010)

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are responsible for excitotoxicity induced by ischemic injury in hippocampal CA1 neurons, whereas the molecular mechanisms r...

Activation of AMPA receptor in the infralimbic cortex facilitates extinction and attenuates the heroin-seeking behavior in rats.

Neurosci. Lett. 612 , 126-31, (2016)

Infralimbic cortex (IL) is proposed to suppress cocaine seeking after extinction, but whether the IL regulates the extinction and reinstatement of heroin-seeking behavior is unknown. To address this i...

The rostromedial tegmental nucleus modulates behavioral inhibition following cocaine self-administration in rats.

Neuropsychopharmacology 40(4) , 861-73, (2015)

Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedia...