2,6-Piperidinedione,4-phenyl-

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Names

[ CAS No. ]:
14149-31-6

[ Name ]:
2,6-Piperidinedione,4-phenyl-

[Synonym ]:
3-Phenylglutarimide
Glutarimide,3-phenyl
4-Phenyl-2,6-piperidinedione
4-phenyl-piperidine-2,6-dione
4-phenylglutarimide
4-Phenyl-piperidin-2,6-dion
4-phenyl-piperidin-2,6-dione

Chemical & Physical Properties

[ Density]:
1.185g/cm3

[ Boiling Point ]:
392.3ºC at 760mmHg

[ Melting Point ]:
173-174℃

[ Molecular Formula ]:
C11H11NO2

[ Molecular Weight ]:
189.21100

[ Flash Point ]:
176.6ºC

[ Exact Mass ]:
189.07900

[ PSA ]:
46.17000

[ LogP ]:
1.53560

[ Vapour Pressure ]:
2.31E-06mmHg at 25°C

[ Index of Refraction ]:
1.553

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MA5350000
CHEMICAL NAME :
Glutarimide, 3-phenyl-
CAS REGISTRY NUMBER :
14149-31-6
BEILSTEIN REFERENCE NO. :
0146423
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H11-N-O2
MOLECULAR WEIGHT :
189.23
WISWESSER LINE NOTATION :
T6VMVTJ ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,243,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

Safety Information

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Phenylglutaric acid
  • Urea
  • 3-Phenylpentanedioic acid
  • 3-Phenylglutaric acid dimethyl ester
  • 4-(aminocarbonyl)-3-phenylbutanoic acid
  • 4-phenyloxane-2,6-dione

DownStream

  • 4-Phenylpiperidine
  • 4-Piperidinecarboxylicacid, 2,6-dioxo-

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • 2,6-Piperidinedione,4-phenyl-1-propyl
  • 2,6-Piperidinedione,4-phenyl-1-(2-propenyl)
  • 2,6-Piperidinedione,4-phenyl-1-(phenylmethyl)
  • 2,6-Piperidinedione,4-ethyl-4-phenyl-
  • 2,6-Piperidinedione,4-methyl-4-phenyl-
  • 2,6-Piperidinedione,4-(4-methoxyphenyl)-1-[(4-phenyl-1-piperazinyl)methyl]-