Dronedarone hydrochloride

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Names

[ CAS No. ]:
141625-93-6

[ Name ]:
Dronedarone hydrochloride

[Synonym ]:
n-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide monohydrochloride
N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide hydrochloride (1:1)
Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)
Multaq Hydrochloride.
Methanesulfonamide, N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-, monohydrochloride
Multaq
Dronedarone (Hydrochloride)
Dronedarone hydrochloride
Dronedarone HCl

Chemical & Physical Properties

[ Boiling Point ]:
683.9ºC at 760mmHg

[ Melting Point ]:
NA (low-melting)

[ Molecular Formula ]:
C31H45ClN2O5S

[ Molecular Weight ]:
593.217

[ Flash Point ]:
367.4ºC

[ Exact Mass ]:
592.273743

[ PSA ]:
97.23000

[ LogP ]:
9.00480

[ Appearance of Characters ]:
white to off-white

[ Vapour Pressure ]:
1.47E-18mmHg at 25°C

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
DMSO: soluble15mg/mL, clear

Safety Information

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

Use of In Vitro Morphogenesis of Mouse Embryoid Bodies to Assess Developmental Toxicity of Therapeutic Drugs Contraindicated in Pregnancy.

Toxicol. Sci. 149 , 15-30, (2016)

In utero exposure to certain chemicals can impair embryo development, causing embryonic death, growth retardation, or severe birth defects. Establishment of effective in vitro tests is crucial for ide...

Inactivation of Human Cytochrome P450 3A4 and 3A5 by Dronedarone and N-Desbutyl Dronedarone.

Mol. Pharmacol. 89 , 1-13, (2015)

Dronedarone is an antiarrhythmic agent approved in 2009 for the treatment of atrial fibrillation. An in-house preliminary study demonstrated that dronedarone inhibits cytochrome P450 (CYP) 3A4 and 3A5...


More Articles

Related Compounds

  • Debutyldronedarone hydrochloride
  • Dronedarone Hydrochloride Impurity B HCl
  • Dronedarone-d6 (hydrochloride)
  • Debutyldronedarone D6 hydrochloride
  • carnitine hydrochloride
  • Losoxantrone hydrochloride [USAN]
  • N1-(2,5-dimethylphenyl)-N2-(2-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)ethyl)oxalamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-biphenyl-3-yl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 1,6-Dimethyl-4-(methylamino)-2-piperidone
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde