Methyl 2-oxoindole-6-carboxylate

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Names

[ CAS No. ]:
14192-26-8

[ Name ]:
Methyl 2-oxoindole-6-carboxylate

[Synonym ]:
Methyl 2-oxoindoline-6-carboxylate
Methyl 2-oxo-6-indolinecarboxylate
T56 BMV DHJ HVO1
methyl 2-oxo-1,3-dihydroindole-6-carboxylate
MFCD03095196
1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester
Methyl oxindole-6-carboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
388.1±42.0 °C at 760 mmHg

[ Melting Point ]:
184-190ºC

[ Molecular Formula ]:
C10H9NO3

[ Molecular Weight ]:
191.183

[ Flash Point ]:
188.5±27.9 °C

[ Exact Mass ]:
191.058243

[ PSA ]:
55.40000

[ LogP ]:
1.53

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 4-(2-methoxy-2-oxoethyl)-3-nitrobenzoate
  • 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
  • Methanol
  • 6-Carboxyoxindole

DownStream

  • 6-Carboxyoxindole
  • Nintedanib (BIBF 1120)
  • 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Related Compounds

  • methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
  • Methyl 2-chloroquinazoline-6-carboxylate
  • methyl 2-aminoquinoline-6-carboxylate
  • Methyl 2-chloroquinoline-6-carboxylate
  • methyl 2-cyanoquinoline-6-carboxylate
  • methyl 2,6-dibutylpiperidine-1-carboxylate
  • 4-[(2s)-2-Aminopropyl]-2-fluorophenol
  • (4-Methoxypyridin-3-yl)methanesulfonamide
  • 6-Amino-1,4-dioxepane-6-carboxylicacid
  • 6-((tert-Butoxycarbonyl)amino)-1,4-dioxepane-6-carboxylic acid
  • 3-Amino-5-fluorophenol;hydrobromide
  • 4-Pyridinemethanamine, 2-bromo-N,-dimethyl-, (R)-
  • (3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-5-yl)methanol
  • 2-Chloro-3,3-bis(phenylamino)-2-propenenitrile
  • 2-(Difluoromethyl)-5-hydrazineyl-1,3,4-thiadiazole
  • Methyl 5-cyano-2-hydroxy-4-methylbenzoate
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