Methyl 2-oxoindole-6-carboxylate

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Names

[ CAS No. ]:
14192-26-8

[ Name ]:
Methyl 2-oxoindole-6-carboxylate

[Synonym ]:
Methyl 2-oxoindoline-6-carboxylate
Methyl 2-oxo-6-indolinecarboxylate
T56 BMV DHJ HVO1
methyl 2-oxo-1,3-dihydroindole-6-carboxylate
MFCD03095196
1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester
Methyl oxindole-6-carboxylate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
388.1±42.0 °C at 760 mmHg

[ Melting Point ]:
184-190ºC

[ Molecular Formula ]:
C10H9NO3

[ Molecular Weight ]:
191.183

[ Flash Point ]:
188.5±27.9 °C

[ Exact Mass ]:
191.058243

[ PSA ]:
55.40000

[ LogP ]:
1.53

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl 4-(2-methoxy-2-oxoethyl)-3-nitrobenzoate
  • 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
  • Methanol
  • 6-Carboxyoxindole

DownStream

  • 6-Carboxyoxindole
  • Nintedanib (BIBF 1120)
  • 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Related Compounds

  • methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
  • Methyl 2-chloroquinazoline-6-carboxylate
  • methyl 2-aminoquinoline-6-carboxylate
  • Methyl 2-chloroquinoline-6-carboxylate
  • methyl 2-cyanoquinoline-6-carboxylate
  • methyl 2,6-dibutylpiperidine-1-carboxylate
  • 6-Hydroxy-2,5,5-trimethylhexanoic acid
  • Methyl 3-(fluoromethyl)tetrahydro-1H-pyrrolizine-7a(5H)-carboxylate
  • 1-[(1R,5R)-2,6-diazabicyclo[3.2.0]heptan-2-yl]-2,2,2-trifluoroethanone
  • 8-(Methylamino)naphthalene-1-sulfonic acid
  • 3-Cyano-5-cyclopropylbenzoic acid
  • Tert-butyl 4-(2,7-dichloro-8-fluoropyrido[4,3-d]pyrimidin-4-yl)piperazine-1-carboxylate
  • 2-methylidene-5-oxo-hexahydro-1H-pyrrolizine-7a-carboxylicacid
  • Ethyl (E)-5,5,5-trifluoro-4-oxopent-2-enoate
  • ((1S,3R,4R)-2-(2,2-Difluoroethyl)-2-azabicyclo[2.2.1]heptan-3-yl)methanol
  • 2,2'-Dichloro-3,3'-difluoro-4,4'-bipyridine
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