Ginsenoside Rg3

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Names

[ CAS No. ]:
14197-60-5

[ Name ]:
Ginsenoside Rg3

[Synonym ]:
β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
20(S)-ginsenoside Rg3
opyransoyl)oxy)
Ginsenoside 20(s)-Rg3
GinsenosideRg3
GINSENOSIDE Rg3(SH)
(20S)-PROPANAXADIOL
MFCD06410950
(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
20S-Ginseniside Rg3
Ginsenoside Rg3
20(S)-Ginsenoside-Rg3

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
885.0±65.0 °C at 760 mmHg

[ Melting Point ]:
315-318°C

[ Molecular Formula ]:
C42H72O13

[ Molecular Weight ]:
785.013

[ Flash Point ]:
489.0±34.3 °C

[ Exact Mass ]:
784.497314

[ PSA ]:
218.99000

[ LogP ]:
5.27

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.594

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LY9537300
CHEMICAL NAME :
beta-D-Glucopyranoside, (3-beta,12-beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D- glucopyranosyl-
CAS REGISTRY NUMBER :
14197-60-5
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C42-H72-O13
MOLECULAR WEIGHT :
785.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,343,1975

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
T,N,Xi

[ Risk Phrases ]:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R33:Danger of cumulative effects. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .

[ Safety Phrases ]:
S28-S36/37-S45-S60-S61-S28A

[ RIDADR ]:
UN 3442 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
CX9862655

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
29214210

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • malonyl-ginsenoside Rb2
  • malonyl-ginsenoside Rc
  • malonylginsenoside Rb1
  • 6''-malonylginsenoside-Rb1 methyl ester

DownStream

  • 20(S)-Ginsenoside Rh2
  • Folienetriol

Customs

[ HS Code ]: 29214210

Articles

Characterization of Panax ginseng UDP-Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rh1 in Metabolically Engineered Yeasts.

Mol. Plant 8 , 1412-24, (2015)

Ginsenosides, the main pharmacologically active natural compounds in ginseng (Panax ginseng), are mostly the glycosylated products of protopanaxadiol (PPD) and protopanaxatriol (PPT). No uridine dipho...

Comparative study on intestinal metabolism and absorption in vivo of ginsenosides in sulphur-fumigated and non-fumigated ginseng by ultra performance liquid chromatography quadruple time-of-flight mass spectrometry based chemical profiling approach.

Drug Test. Anal. 7(4) , 320-30, (2015)

Our previous study indicated that sulphur-fumigation of ginseng in post-harvest handling processes could induce chemical transformation of ginsenosides to generate multiple ginsenoside sulphur derivat...

Red ginseng extract promotes the hair growth in cultured human hair follicles.

J. Med. Food 18(3) , 354-62, (2015)

Ginseng has been shown to promote hair growth in several recent studies. However, its effects on human hair follicles and its mechanisms of action have not been sufficiently elucidated. This study aim...


More Articles

Related Compounds

  • Ginsenoside Rg3
  • Ginsenoside Rg3
  • S-GINSENOSIDE RG3
  • Ginsenoside Rg3 Rh2
  • Pseudoginsenoside Rg3
  • Ginsenoside R1
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