N-(2-Hydroxyethyl)acetamide

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Names

[ CAS No. ]:
142-26-7

[ Name ]:
N-(2-Hydroxyethyl)acetamide

[Synonym ]:
N-acetyl-N-(2-hydroxyethyl)amine
ACETYLETHANOLAMINE
2-Acetylaminoethanol
N-Acetylethanolamine
MFCD00002836
N-(2-hydroxyethyl)-acetamide
Acetamide,N-(2-hydroxyethyl)
N-Acetyl-2-aminoethanol
N-Ethanolacetamide
N-acetyl aminoethanol
EINECS 205-530-8
N-(2-Hydroxyethyl)acetamide
Acetylcolamine
2-Acetamidoethanol

Chemical & Physical Properties

[ Density]:
1.12 g/mL at 25 °C(lit.)

[ Boiling Point ]:
151-155 °C5 mm Hg(lit.)

[ Melting Point ]:
15.8 °C

[ Molecular Formula ]:
C4H9NO2

[ Molecular Weight ]:
103.12000

[ Flash Point ]:
350 °F

[ Exact Mass ]:
103.06300

[ PSA ]:
49.33000

[ Vapour Pressure ]:
0.00021mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.472(lit.)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC3120000
CHEMICAL NAME :
Acetamide, N-(2-hydroxyethyl)-
CAS REGISTRY NUMBER :
142-26-7
BEILSTEIN REFERENCE NO. :
1811708
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-N-O2
MOLECULAR WEIGHT :
103.14
WISWESSER LINE NOTATION :
Q2MV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/21/1967
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12(3),225,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>20 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/21/1967

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R37/38;R41

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
AC3120000

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

  • Methyl acetate
  • 2-Aminoethanol
  • ethyl acetate
  • Ethanoic anhydride
  • Isopropyl acetate
  • acetic acid
  • Benzyl acetate
  • tert-Butyl acetate
  • Acetyl chloride
  • 3-Acetylthiazolidine-2-thione

DownStream

  • Acetamide,N-[2-(4-nitrophenoxy)ethyl]-
  • 2-[(2,4-dinitrophenyl)amino]ethyl acetate
  • Acetamide
  • ch3cho
  • 2-Thiazoline, 2-methyl-
  • N-(2-CHLOROETHYL)ACETAMIDE
  • N-(2-(4-bromopyridin-2-yloxy)ethyl)acetamide
  • 2-Methyl-2-oxazoline
  • Acetamide,N-[2-(dimethylamino)ethyl]-
  • 2-OXAZOLIDINONE, 3-ACETYL-

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • Chloro-N-(2-hydroxyethyl)acetamide
  • 2-Cyano-N-(2-hydroxyethyl)acetamide
  • 2-amino-N-(2-hydroxyethyl)acetamide
  • N-benzyl-N-(2-hydroxyethyl)acetamide
  • N-acetyl-N-(2-hydroxyethyl)acetamide
  • 2-hydroxy-N-(2-hydroxyethyl)acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-(2-Chloro-4-nitrophenyl)hydrazinecarbothioamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide