Niclosamide olamine

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Names

[ CAS No. ]:
1420-04-8

[ Name ]:
Niclosamide olamine

[Synonym ]:
Luomiecide
Hl 2448
MFCD01941566
EINECS 215-811-7
Mollutox
2',5-dichloro-4'-nitrosalicylanilide
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide - 1-propanamine (1:1)
Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-, compd. with 1-propanamine (1:1)
clonitralid
Niclosamide ethanolamine salt
2’,5-dichloro-4’-nitrosalicylanilide - 2-aminoethanol (1:1)
BAYER73
(2-hydroxyethyl)ammonium 4-chloro-2-[(2-chloro-4-nitroanilino)carbonyl]phenolate
BAY-73
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide—2-aminoethan-1-ol
Snanilcide
BAYER-6076
Clonitralide
NICLOSAMIDEL
5,2'-dichloro-4'-nitro-salicylanilide ethanolamine salt
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide compound with 2-aminoethanol (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
155-156 °C

[ Melting Point ]:
91-93 °C(lit.)

[ Molecular Formula ]:
C15H15Cl2N3O5

[ Molecular Weight ]:
386.230

[ Flash Point ]:
149 °F

[ Exact Mass ]:
385.059601

[ PSA ]:
141.40000

[ LogP ]:
4.09340

[ Stability ]:
Stable. Hydrolyzes in concentrated acidic or basic solutions.

[ Water Solubility ]:
soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN8575000
CAS REGISTRY NUMBER :
1420-04-8
LAST UPDATED :
199607
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C13-H8-Cl2-N2-O4.C2-H7-N-O
MOLECULAR WEIGHT :
388.23
WISWESSER LINE NOTATION :
WNR CG DMVR BQ EG &Z2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 3,103,1976/1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,126,1973 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
336600 ug/kg
SEX/DURATION :
female 5-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 53,1,1995 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

[ Safety Phrases ]:
S16-S26-S36/37/39-S45

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1


Related Compounds

  • Niclosamide
  • niclosamide piperazine salt
  • Niclosamide (monohydrate)
  • niclosamide sodium salt
  • NiclosaMide-13C6 hydrate (see Data Sheet)
  • Niclosamide-13C6 monohydrate
  • 4-(Difluoromethyl)thiophene-3-carboxylic acid
  • 3-Pyridinemethanamine, I+/-,4,6-trimethyl-
  • 5-Fluoro-2-(2H-1,2,3-triazol-2-yl)aniline
  • 2-Fluoro-5-(2H-1,2,3-triazol-2-yl)benzenamine
  • Imidazo[1,5-a]pyridine-6-methanamine, 5,6,7,8-tetrahydro-
  • {5H,6H,7H,8H-imidazo[1,5-a]pyridin-8-yl}methanamine
  • 3-[(1H-indol-3-yl)methyl]pyrrolidin-3-ol
  • Methyl 2-(4-oxooxan-3-yl)acetate
  • N-([2,3a(2)-Bipyridin]-3-ylmethyl)-Na(2)-(2,3-dichlorophenyl)thiourea
  • 2-{Imidazo[1,2-a]pyridin-3-yl}propan-1-amine
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