dpx
Names
Chemical & Physical Properties
[ Density]:
0.904 g/mL at 25ºC(lit.)
[ Molecular Formula ]:
C18H18Br2N2
[ Molecular Weight ]:
422.15700
[ Flash Point ]:
77 °F
[ Exact Mass ]:
419.98400
[ PSA ]:
7.76000
[ Appearance of Characters ]:
white to off-white
[ Index of Refraction ]:
n20/D 1.521(lit.)
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
H2O: soluble
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU6857800
- CHEMICAL NAME :
- Pyridinium, 1,1'-(p-phenylenedimethylene)bis-, dibromide
- CAS REGISTRY NUMBER :
- 14208-10-7
- LAST UPDATED :
- 198609
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H18-N2.2Br
- MOLECULAR WEIGHT :
- 422.20
- WISWESSER LINE NOTATION :
- T6KJ A1R D1- AT6KJ &E 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 114,217,1958
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;T: Toxic;
[ Risk Phrases ]:
R10
[ Safety Phrases ]:
26-36-45-36/37-53
[ RIDADR ]:
UN 1307 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
UU6857800
[ HS Code ]:
2933399090
Synthetic Route
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Neurosci. 35(6) , 2384-97, (2015)
Both estrous cycle and sex affect the numbers and types of neuronal and glial profiles containing the classical estrogen receptors α and β, and synaptic levels in the rodent dorsal hippocampus. Here, ...
PLoS ONE 10(4) , e0123553, (2015)
Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facil...
Kidney Int. 88 , 52-60, (2015)
Spleen tyrosine kinase (SYK) is an important component of the intracellular signaling pathway for various immunoreceptors. Inhibition of SYK has shown promise in preclinical models of autoimmune and g...