Amthamine dihydrobromide

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Names

[ CAS No. ]:
142457-00-9

[ Name ]:
Amthamine dihydrobromide

[Synonym ]:
cc-388
Amthamine dihydrobromide
Hispidulin
2-amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide
2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide

Chemical & Physical Properties

[ Molecular Formula ]:
C6H13Br2N3S

[ Molecular Weight ]:
319.06

[ Exact Mass ]:
316.92000

[ PSA ]:
93.90000

[ LogP ]:
3.08150

MSDS

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Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

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Precursor & DownStream

Precursor

  • 5-Chloro-2-pentanone
  • 1- Phthalimido-4-pentanone
  • 3-bromo-5-phtalimido-2-pentanone

DownStream

Articles

Modulation of in vivo immunoglobulin production by endogenous histamine and H1R and H2R agonists and antagonists.

Pharmacol. Rep. 62(5) , 917-25, (2010)

The present study was designed to delineate the immunomodulatory role of histamine receptors (H1R and H2R) and their antibody generation in a rabbit model. Six groups containing 18 rabbits each receiv...

Analysis of the histamine H2-receptor in human monocytes.

Biochem. Pharmacol. 92(2) , 369-79, (2014)

Histamine receptors are G-protein-coupled receptors (GPCRs). Canonically, the histamine H2-receptor (H2R) couples to Gs-proteins and activates adenylyl cyclases (ACs) with subsequent adenosine-3',5'-c...

Disruption of histamine H2 receptor slows heart failure progression through reducing myocardial apoptosis and fibrosis.

Clin. Sci. 127(7) , 435-48, (2014)

Histamine H2 receptor (H2R) blockade has been reported to be beneficial for patients with chronic heart failure (CHF), but the mechanisms involved are not entirely clear. In the present study, we asse...


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Related Compounds

  • Amthamine dihydrobromide
  • Amthamine
  • Hydrazine Dihydrobromide Hydrate
  • piperazine dihydrobromide
  • VP3.15 dihydrobromide
  • quinine dihydrobromide
  • 5-Tert-butyl-2-cyclopropoxy-N-methylaniline
  • 3-Cyclopropoxy-6-(methylamino)pyridine-2-sulfonamide
  • 2-Cyclopropoxy-N-methyl-5-(methylamino)benzamide
  • 2-Tert-butyl-3-cyclopropoxy-6-methoxypyridine
  • 5-Cyclopropoxy-6-methoxy-N-methylpyridin-2-amine
  • 1-Cyclopropoxy-2-methoxy-4-methylbenzene
  • 1-Bromo-3-cyclopropoxy-5-methoxybenzene
  • 1-Cyclopropoxy-4-methoxy-2-methylbenzene
  • 2-(6-Bromo-2,7-dimethyl-2,3-dihydro-1,4-benzoxazin-4-YL)-N-(cyanomethyl)acetamide
  • 3-Cyclopropoxy-N,N-dimethyl-4-(methylthio)picolinamide