Lauric acid
Suppliers
Names
[ CAS No. ]:
143-07-7
[ Name ]:
Lauric acid
[Synonym ]:
EINECS 205-582-1
Lauric acid
MFCD00002736
Dodecanoic Acid
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
296.1±3.0 °C at 760 mmHg
[ Melting Point ]:
44-46 °C(lit.)
[ Molecular Formula ]:
C12H24O2
[ Molecular Weight ]:
200.318
[ Flash Point ]:
134.1±11.9 °C
[ Exact Mass ]:
200.177628
[ PSA ]:
37.30000
[ LogP ]:
5.03
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.448
[ Stability ]:
Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OE9800000
- CHEMICAL NAME :
- Lauric acid
- CAS REGISTRY NUMBER :
- 143-07-7
- BEILSTEIN REFERENCE NO. :
- 1099477
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C12-H24-O2
- MOLECULAR WEIGHT :
- 200.36
- WISWESSER LINE NOTATION :
- QV11
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 131 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 333 gm/kg/13W-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Behavioral - fluid intake
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 108 gm/kg/15W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 294,263,1981 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84696 No. of Facilities: 1256 (estimated) No. of Industries: 14 No. of Occupations: 34 No. of Employees: 14960 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84696 No. of Facilities: 4690 (estimated) No. of Industries: 51 No. of Occupations: 50 No. of Employees: 77970 (estimated) No. of Female Employees: 17300 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H318
[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
OE9800000
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915900090
[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
Articles
AAPS J. 16(4) , 875-83, (2014)
The effect of food intake on the release and degradation of peptide drugs from solid lipid particles is unknown and was therefore investigated in vitro using different fed state media in a lipolysis m...
Appl. Microbiol. Biotechnol. 99(5) , 2291-304, (2015)
Volatile compounds produced by yeast during fermentation greatly influence the organoleptic qualities of wine. We developed a model to predict the combined effects of initial nitrogen and phytosterol ...
Orig. Life Evol. Biosph. 45 , 427-37, (2015)
Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino ...