hydrocodone bitartrate

Suppliers

Names

[ CAS No. ]:
143-71-5

[ Name ]:
hydrocodone bitartrate

[Synonym ]:
Robidone
EINECS 205-608-1
Synkonin
MFCD00078557
Codone
Dicotrate
Dicodrine
Dicodethal
Stodcodon
Biocodone
4,5-epoxy-3-methoxy-17-methylmorphinan-6-one bitartrate
Hycon
hydrocodone ditartrate
Hydrokon

Chemical & Physical Properties

[ Boiling Point ]:
461.4ºC at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₇NO₉

[ Molecular Weight ]:
449.45100

[ Flash Point ]:
232.9ºC

[ Exact Mass ]:
449.16900

[ PSA ]:
153.83000

[ Vapour Pressure ]:
1.07E-08mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 62 mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
23/25-36/38

[ Safety Phrases ]:
S7;S16;S24;S33;S45

[ RIDADR ]:
UN 1230 3/PG 2

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats.

J. Pharmacol. Exp. Ther. 280 , 1374-1382, (1997)

Humans that lack cytochrome P450 2D6 (CYP2D6) activity may have an altered risk of drug dependence or abuse because this enzyme is important in the metabolism of some drugs of abuse, including hydroco...

Mu receptor binding of some commonly used opioids and their metabolites.

Life Sci. 48 , 2165-2171, (1991)

The binding affinity to the mu receptor of some opioids chemically related to morphine and some of their metabolites was examined in rat brain homogenates with 3H-DAMGO. The chemical group at position...

The antitussive activity of delta-opioid receptor stimulation in guinea pigs.

J. Pharmacol. Exp. Ther. 292 , 803-809, (2000)

In this study, the activity of the delta-opioid receptor subtype-selective agonist, SB 227122, was investigated in a guinea pig model of citric acid-induced cough. Parenteral administration of selecti...