(3S,7aR)-7a-methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b][1,3]oxazol-5-one

Names

[ CAS No. ]:
143140-06-1

[ Name ]:
(3S,7aR)-7a-methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b][1,3]oxazol-5-one

[Synonym ]:
(3S-cis)-(+)-2,3-Dihydro-7a-methyl-3-phenylpyrrolo[2,1-b]oxazol-5(7aH)-one
(3S,7aR)-7a-methyl-3-phenyl-2H,3H-3-pyrrolino[2,1-b]1,3-oxazolidin-5-one
MFCD00274331

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
410ºC at 760mmHg

[ Melting Point ]:
88-92ºC

[ Molecular Formula ]:
C13H13NO2

[ Molecular Weight ]:
215.24800

[ Flash Point ]:
201.7ºC

[ Exact Mass ]:
215.09500

[ PSA ]:
29.54000

[ LogP ]:
1.81040

[ Vapour Pressure ]:
6.24E-07mmHg at 25°C

[ Index of Refraction ]:
1.624

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

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Precursor & DownStream

Precursor

  • (S)-(+)-2-Phenylglycinol
  • Levulinic acid
  • (3r-cis)-7a-methyl-3-phenyltetrahydropyrrolo[2,1-b]oxazol-5(6h)-one

DownStream

Articles

A Rapid and Efficient Approach to Chiral, Nonracemic Aza Sugars from Nonsugars. A Formal Synthesis of 1,4-Dideoxy-1,4-imino-D-lyxitol.

J. Org. Chem. 61 , 2586, (1996)

Romo, D. Meyers, A.I.

Tetrahedron 47 , 9503, (1991)

Fray, A.H. Meyers, A.I.

J. Org. Chem. 61 , 3362, (1996)


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