(2R,3S)-3-Phenylisoserine ethyl ester

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Names

[ CAS No. ]:
143615-00-3

[ Name ]:
(2R,3S)-3-Phenylisoserine ethyl ester

[Synonym ]:
ethyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropionate
(2R,3S)-3-amino-2-hydroxyl-3-phenylpropanoic acid hydrochloride
(2R,3S)-3-Phenylisoserine HCl
Ethyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate
(2R,3S)-3-Amino-2-hydroxy-3-phenyl propionic acid-hydrochloride
(2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid hydrochloride
(2R,3S)-3-phenylisoserine hydrochloride
phenylisoserine hydrochloride
Benzenepropanoic acid, β-amino-α-hydroxy-, ethyl ester, (αR,βS)-
(2R,3S)-phenylisoserine hydrochloride
(2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid ethyl ester
(2R,3S)-3-amino-2-hydroxyl-3-phenylpropionic acid ethyl ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
355.3±42.0 °C at 760 mmHg

[ Melting Point ]:
82-84℃

[ Molecular Formula ]:
C11H15NO3

[ Molecular Weight ]:
209.242

[ Flash Point ]:
168.7±27.9 °C

[ Exact Mass ]:
209.105194

[ PSA ]:
72.55000

[ LogP ]:
1.42

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.549

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl 3-Azido-2-hydroxy-propionate
  • ethyl (2R,3S)-3-{[(R)-1-phenylethyl]amino}-2-hydroxy-3-phenylpropanoate
  • Ethanol
  • (2R,3S)-3-Phenylisoserine hydrochloride
  • Benzaldehyde
  • Ethyl 3-phenyl-2-oxiranecarboxylate

DownStream

  • N-(t-Boc)-3-phenyl Isoserine Ethyl Ester
  • 13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
  • 3-(t-Boc)-2,2-dimethyl-4-phenyl-1,3-oxazolidin-5-yl]formic Acid Ethyl Ester
  • Paclitaxel
  • 7,10-di-Troc-Docetaxel
  • N-Benzoyl-(2R,3S)-3-phenylisoserine
  • (2R,3S)-3-Phenylisoserine hydrochloride
  • (2R,3S)-3-PHENYLISOSERINE ETHYLESTER
  • N-Des-t-boc-10-deacetyl-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl} Docetaxel

Related Compounds

  • (2R,3S)-3-PHENYLISOSERINE ETHYLESTER
  • (2R,3S)-3-Phenylisoserine hydrochloride
  • (2R,3S)-3-Phenylisoserine
  • (2R,3S)-3-phenylisoserine methyl ester acetate
  • (2R,3S)-3-phenylisoserine methyl ester
  • N-Benzoyl-(2R,3S)-3-phenylisoserine
  • N4-(2-aminoethyl)-N6,N6-dimethylpyrimidine-4,6-diamine
  • 5-Cyclopropyl-2-(1,1-dimethoxyethyl)thiazole
  • 1-[4-(5-Bromo-3-pyridinyl)-1-piperidinyl]-1-propanone
  • 3-Hydroxy-3-methyl-4-pentyn-1-yl perfluoro-2-[2-(propoxy)propoxy]propanoate
  • Allyl (3-(5-(2-chloropyrimidin-4-yl)-2-phenylthiazol-4-yl)-2-fluorophenyl)carbamate
  • 1-Piperidineacetamide, 3-ethyl-4-(hydroxyimino)-I+/--methyl-N-(1-methylethyl)-
  • 3-[1-(Aminomethyl)cyclohexyl]-4-bromophenol
  • 3-(5-Chloro-2-pyridyl)-5-methylisoxazole-4-carboxylic Acid
  • 2-(4-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride
  • Sodium 2-bromo-4-fluoro-5-nitrobenzene-1-sulfinate
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