(2R,3S)-3-Phenylisoserine ethyl ester

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Names

[ Name ]:
(2R,3S)-3-Phenylisoserine ethyl ester

[Synonym ]:
ethyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropionate
(2R,3S)-3-amino-2-hydroxyl-3-phenylpropanoic acid hydrochloride
(2R,3S)-3-Phenylisoserine HCl
Ethyl (2R,3S)-3-amino-2-hydroxy-3-phenylpropanoate
(2R,3S)-3-Amino-2-hydroxy-3-phenyl propionic acid-hydrochloride
(2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid hydrochloride
(2R,3S)-3-phenylisoserine hydrochloride
phenylisoserine hydrochloride
Benzenepropanoic acid, β-amino-α-hydroxy-, ethyl ester, (αR,βS)-
(2R,3S)-phenylisoserine hydrochloride
(2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid ethyl ester
(2R,3S)-3-amino-2-hydroxyl-3-phenylpropionic acid ethyl ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
355.3±42.0 °C at 760 mmHg

[ Melting Point ]:
82-84℃

[ Molecular Formula ]:
C₁₁H₁₅NO₃

[ Molecular Weight ]:
209.242

[ Flash Point ]:
168.7±27.9 °C

[ Exact Mass ]:
209.105194

[ PSA ]:
72.55000

[ LogP ]:
1.42

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.549

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethyl 3-Azido-2-hydroxy-propionate
ethyl (2R,3S)-3-{[(R)-1-phenylethyl]amino}-2-hydroxy-3-phenylpropanoate
Ethanol
(2R,3S)-3-Phenylisoserine hydrochloride
Benzaldehyde
Ethyl 3-phenyl-2-oxiranecarboxylate

DownStream

N-(t-Boc)-3-phenyl Isoserine Ethyl Ester
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
3-(t-Boc)-2,2-dimethyl-4-phenyl-1,3-oxazolidin-5-yl]formic Acid Ethyl Ester
Paclitaxel
7,10-di-Troc-Docetaxel
N-Benzoyl-(2R,3S)-3-phenylisoserine
(2R,3S)-3-Phenylisoserine hydrochloride
(2R,3S)-3-PHENYLISOSERINE ETHYLESTER
N-Des-t-boc-10-deacetyl-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl} Docetaxel

Related Compounds

(2R,3S)-3-PHENYLISOSERINE ETHYLESTER
(2R,3S)-3-Phenylisoserine hydrochloride
(2R,3S)-3-Phenylisoserine
(2R,3S)-3-phenylisoserine methyl ester acetate
(2R,3S)-3-phenylisoserine methyl ester
N-Benzoyl-(2R,3S)-3-phenylisoserine
Methyl 6-bromo-3-(bromomethyl)pyridine-2-carboxylate
Methyl 3-(bromomethyl)-6-methoxypyridine-2-carboxylate
Methyl 3-(bromomethyl)-5-chloropicolinate
Methyl 2-acetyl-6-chloroisonicotinate
(4,6-Dimethoxypyridin-3-YL)methanamine
1-(6-Cyclopropylpyridin-3-YL)ethan-1-one
2-(6-Chloro-4-(trifluoromethyl)pyridin-3-yl)ethan-1-amine
(6-Chloro-3-(trifluoromethyl)pyridin-2-yl)methanamine
(5-Bromo-3-cyclopropoxypyridin-2-YL)methanamine
1-(3-Chloro-4-(trifluoromethyl)pyridin-2-yl)ethan-1-one

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