1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylene-dioxy-3,4-dihydro-5H-2,3-benzodiazepine

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Names

[ CAS No. ]:
143692-40-4

[ Name ]:
1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylene-dioxy-3,4-dihydro-5H-2,3-benzodiazepine

Chemical & Physical Properties

[ Boiling Point ]:
528.9ºC at 760mmHg

[ Molecular Formula ]:
C19H20ClN3O3

[ Molecular Weight ]:
373.83300

[ Flash Point ]:
273.7ºC

[ Exact Mass ]:
373.11900

[ PSA ]:
77.15000

[ LogP ]:
3.29970

[ Vapour Pressure ]:
2.84E-11mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JI4632000
CHEMICAL NAME :
7H-1,3-Dioxolo(4,5-h)(2,3)benzodiazepine, 8,9-dihydro-7-acetyl-5-(4-aminophenyl)-8-methyl-, monohydrochloride
CAS REGISTRY NUMBER :
143692-40-4
LAST UPDATED :
199606
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H19-N3-O3.Cl-H
MOLECULAR WEIGHT :
373.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0492485
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0492485

Related Compounds

  • (1-{2-[Methyl(propan-2-yl)amino]ethyl}cyclopropyl)methanamine
  • N-[(1R)-1-phenylethyl]cyclobutanamine
  • 3-Pyridinol, 2-fluoro-6-iodo-
  • (S)-N-(1-Phenylethyl)cyclobutanamine
  • 3-(2,2-Difluoroethoxy)propan-1-ol
  • 1-[2-Bromo-1-(2,2-difluoroethoxy)ethyl]-3-methylbenzene
  • 2-Fluoro-5-(isocyanomethyl)benzonitrile
  • 4-Bromo-2-(2,2-difluoroethoxy)benzaldehyde
  • 2-(2,2-Difluoroethoxy)acetonitrile
  • (1R,3S)-3-(Hydroxymethyl)cyclopentan-1-ol
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