7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one
Names
[ CAS No. ]:
144485-81-4
[ Name ]:
7-chloro-3-(3-methyl-1,2-oxazol-5-yl)-2-phenylquinazolin-4-one
Chemical & Physical Properties
[ Density]:
1.4g/cm3
[ Boiling Point ]:
557.6ºC at 760mmHg
[ Molecular Formula ]:
C18H12ClN3O2
[ Molecular Weight ]:
337.76000
[ Flash Point ]:
291ºC
[ Exact Mass ]:
337.06200
[ PSA ]:
60.92000
[ LogP ]:
4.00250
[ Vapour Pressure ]:
1.81E-12mmHg at 25°C
[ Index of Refraction ]:
1.69
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA2807010
- CHEMICAL NAME :
- 4(3H)-Quinazolinone, 7-chloro-3-(3-methyl-5-isoxazolyl)-2-phenyl-
- CAS REGISTRY NUMBER :
- 144485-81-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H12-Cl-N3-O2
- MOLECULAR WEIGHT :
- 337.78
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992