2,7-dimethyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Names

[ CAS No. ]:
144485-91-6

[ Name ]:
2,7-dimethyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
470.9ºC at 760 mmHg

[ Molecular Formula ]:
C14H13N3O2

[ Molecular Weight ]:
255.27200

[ Flash Point ]:
238.6ºC

[ Exact Mass ]:
255.10100

[ PSA ]:
60.92000

[ LogP ]:
2.29890

[ Vapour Pressure ]:
4.85E-09mmHg at 25°C

[ Index of Refraction ]:
1.655

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3315610
CHEMICAL NAME :
4(3H)-Quinazolinone, 2,7-dimethyl-3-(3-methyl-5-isoxazolyl)-
CAS REGISTRY NUMBER :
144485-91-6
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H13-N3-O2
MOLECULAR WEIGHT :
255.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Methyl-2-nitrobenzoyl chloride

DownStream

Related Compounds

  • N-[(4-bromo-3-ethyl-1-methyl-1H-pyrazol-5-yl)methyl]-N-methylsulfamoylfluoride
  • N-(4-amino-2,3-dihydro-1H-inden-1-yl)cyclopropanecarboxamide
  • 3-amino-N-ethylpropane-1-sulfonamide hydrochloride
  • 1-cyclopropyl-5-iodo-1H-1,2,3,4-tetrazole
  • 2-[(1-Acetylpyrrolidin-3-yl)amino]acetic acid dihydrochloride
  • 1-bromo-5H,6H,7H,8H-imidazo[1,5-a]pyridine-3-carboxylic acid hydrochloride
  • 2,2,7,7-Tetramethyl-1,4-thiazepan-5-one
  • Methyl 2-trifluoromethanesulfinylacetate
  • 5-Fluoro-4-(piperidin-4-yl)pyrimidin-2-amine dihydrochloride
  • 5-Fluoro-4-(piperidin-4-yl)pyrimidin-2-amine
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