1,1,1-Trimethoxyethane

Names

[ Name ]:
1,1,1-Trimethoxyethane

[Synonym ]:
EINECS 215-892-9
1,1,1-Trimethoxyethane
Orthoacetic Acid Trimethyl Ester
Ethane, 1,1,1-trimethoxy-
Trimethyl orthoacetate
MFCD00008477

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
108.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-58ºC

[ Molecular Formula ]:
C₅H₁₂O₃

[ Molecular Weight ]:
120.147

[ Flash Point ]:
16.7±0.0 °C

[ Exact Mass ]:
120.078644

[ PSA ]:
27.69000

[ LogP ]:
0.90

[ Vapour Pressure ]:
30.9±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.384

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
HYDROLYSIS

MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R38;R43

[ Safety Phrases ]:
S16-S37/39-S24

[ RIDADR ]:
UN 3272 3/PG 2

[ WGK Germany ]:
1

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methyl acetate
Trimethyl orthoformate
Methanol
Diethyl ether
1-((2-chloroethyl)oxy)ethanimine hydrochloride
1,1-dichloro-1-nitroethane
Sodium Methylate
Methyl ethanimidate hydrochloride (1:1)
1,1-Dimethoxyethylene
ch3cho

DownStream

METHYL 1-METHYL-1,2,3-TRIAZOLE-5-CARBOXYLATE
METHYL 2-METHYL-2H-1,2,3-TRIAZOLE-4-CARBOXYLATE
N,N'-di(propan-2-yl)ethanimidamide
6-FLUORO-2-METHYLBENZOXAZOLE
Sucralose
2-(Carbomethoxy)thiophene
2,5,6-Trimethyl-1H-benzimidazole
Methyl 4-fluoro-3-nitrobenzoate
Methyl vanillate
3-methoxypropene

Customs

[ HS Code ]: 2909199090

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Kinetics and mechanisms of the homogeneous, unimolecular gas-phase elimination of trimethyl orthoacetate and trimethyl orthobutyrate.

J. Phys. Chem. A 112(47) , 12140-2, (2008)

The gas-phase elimination kinetics of the title compounds have been examined over the temperature range of 310-369 degrees C and pressure range of 50-130 Torr. The reactions, in seasoned vessels, are ...

Synthesis and evaluation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyloxymethyl-4-alkoxycarbonyloxybut-1- yl)purines as potential prodrugs of penciclovir.

Bioorg. Med. Chem. 7(8) , 1715-25, (1999)

A series of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purin es (1-8) and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines (9-12) were synthesized as potential pr...