GR113808

Suppliers

Names

[ CAS No. ]:
144625-51-4

[ Name ]:
GR113808

[Synonym ]:
Clocinnamox mesylate
MFCD00912901
1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
572.3ºC at 760 mmHg

[ Molecular Formula ]:
C19H27N3O4S

[ Molecular Weight ]:
393.50000

[ Flash Point ]:
299.9ºC

[ Exact Mass ]:
393.17200

[ PSA ]:
89.02000

[ LogP ]:
3.00590

[ Vapour Pressure ]:
4.19E-13mmHg at 25°C

[ Index of Refraction ]:
1.613

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

Bioorg. Med. Chem. 17 , 2607-2622, (2009)

Based on the definition of a 5-HT(4) receptor antagonist pharmacophore, a series of pyrrolo[1,2-a]thieno[3,2-e] and pyrrolo[1,2-a]thieno[2,3-e] pyrazine derivatives were designed, prepared, and evalua...

Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

Pharmacol. Res. 66(3) , 226-34, (2012)

Serotonin (5-HT) exerts multiple physiological functions not only in the central and peripheral nervous systems but also in the gastrointestinal tract, and these multiple functions are accounted for b...

Molecular characterization of a purified 5-HT4 receptor: a structural basis for drug efficacy.

J. Biol. Chem. 280(21) , 20253-60, (2005)

Serotonin 5-HT(4(a)) receptor, a G-protein-coupled receptor (GPCR), was produced as a functional isolated protein using Escherichia coli as an expression system. The isolated receptor was characterize...


More Articles

Related Compounds

  • 1-Fluoro-2,3-dimethoxy-4-methylbenzene
  • 2-{[1-(2-{[1,1'-biphenyl]-4-yl}acetyl)piperidin-4-yl]methyl}-2H,3H,5H,6H,7H-cyclopenta[c]pyridazin-3-one
  • 1-(2-Bromo-5-methoxyphenyl)-1-chloropropan-2-one
  • 2-Fluoro-6-methyl-3-(trifluoromethoxy)aniline
  • CID 137916872
  • Ethyl 5,5-dimethoxypiperidine-3-carboxylate
  • (2-Methylidenecyclopropyl)methanamine;hydrochloride
  • 3-{[1-({4H,5H,6H-cyclopenta[d][1,3]thiazol-2-yl}methyl)piperidin-4-yl]methoxy}-6-cyclopropylpyridazine
  • 3-(2,5-Dihydroxyphenyl)propanenitrile
  • (R)-6-Bromo-5-chloro-1,2,3,4-tetrahydronaphthalen-1-amine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.