GR113808

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Names

[ CAS No. ]:
144625-51-4

[ Name ]:
GR113808

[Synonym ]:
Clocinnamox mesylate
MFCD00912901
1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
572.3ºC at 760 mmHg

[ Molecular Formula ]:
C19H27N3O4S

[ Molecular Weight ]:
393.50000

[ Flash Point ]:
299.9ºC

[ Exact Mass ]:
393.17200

[ PSA ]:
89.02000

[ LogP ]:
3.00590

[ Vapour Pressure ]:
4.19E-13mmHg at 25°C

[ Index of Refraction ]:
1.613

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.

Bioorg. Med. Chem. 17 , 2607-2622, (2009)

Based on the definition of a 5-HT(4) receptor antagonist pharmacophore, a series of pyrrolo[1,2-a]thieno[3,2-e] and pyrrolo[1,2-a]thieno[2,3-e] pyrazine derivatives were designed, prepared, and evalua...

Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

Pharmacol. Res. 66(3) , 226-34, (2012)

Serotonin (5-HT) exerts multiple physiological functions not only in the central and peripheral nervous systems but also in the gastrointestinal tract, and these multiple functions are accounted for b...

Molecular characterization of a purified 5-HT4 receptor: a structural basis for drug efficacy.

J. Biol. Chem. 280(21) , 20253-60, (2005)

Serotonin 5-HT(4(a)) receptor, a G-protein-coupled receptor (GPCR), was produced as a functional isolated protein using Escherichia coli as an expression system. The isolated receptor was characterize...


More Articles

Related Compounds

  • 2-(5-Oxo-hexyl)-oxazole-4-carbonyl chloride
  • 2-Ethyl-1-[2-(1-piperidinyl)ethyl]-1H-benzimidazol-4-amine
  • 1-(3-Amino-4-methylphenyl)-2-morpholin-4-ylethanone
  • Tetradecanoic acid, 2,3-dihydroxyheptadecyl ester
  • 4-Amino-N-butyl-2-(methoxymethyl)-N-methyl-1H-benzimidazole-1-acetamide
  • 1-Methyl-2-(trifluoromethyl)benzimidazol-4-amine
  • 5-Bromo-2-(3-methoxyazetidin-1-yl)pyridine
  • (3R,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
  • Ethyl 5-(1-cyclopropylethyl)-1,2,4-oxadiazole-3-carboxylate
  • Phosphoramidic acid, [2-(2-chlorophenyl)ethenyl]methyl-, diethyl ester
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