Hispidulin

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Names

[ CAS No. ]:
1447-88-7

[ Name ]:
Hispidulin

[Synonym ]:
Dinatin
Scutellarein 6-methyl ether
6-O-Methylapigenin
TCMDC-123942
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
4',5,7-Trihydroxy-6-methoxyflavone
5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
Hispidulin
6-O-Methoxyapigenin
5,7,4'-trihydroxy-6-methoxyflavone
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
Flavone, 4',5,7-trihydroxy-6-methoxy-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
601.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H12O6

[ Molecular Weight ]:
300.263

[ Flash Point ]:
230.1±25.0 °C

[ Exact Mass ]:
300.063385

[ PSA ]:
100.13000

[ LogP ]:
1.60

[ Appearance of Characters ]:
white to beige

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.697

[ Storage condition ]:
Desiccate at -20°C

[ Water Solubility ]:
DMSO: soluble20mg/mL, clear

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DJ2996000

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Xanthoxylin
  • 4-(benzyloxy)benzoyl chloride
  • 2',4',6'-Trihydroxyacetophenone Monohydrate
  • 4'-Benzyloxy-6'-hydroxy-2',3'-dimethoxyacetophenone
  • 2',4'-Dihydroxy-6'-methoxyacetophenone
  • 4-(Benzyloxy)benzoic acid
  • 1-(4-(benzyloxy)-3,6-dihydroxy-2-Methoxyphenyl)ethanone
  • 1-(4-BENZYLOXY-2-HYDROXY-6-METHOXY-PHENYL)-ETHANONE
  • 4-Hydroxybenzoic acid
  • Homoplantaginin

DownStream

  • [2-acetyloxy-4-(5,7-diacetyloxy-4-oxochromen-2-yl)phenyl] acetate
  • Scutellarein

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Analysis of vervain flavonoids by HPLC/Diode array detector method. Its application to quality control.

J. Agric. Food Chem. 47(11) , 4579-82, (1999)

A reversed-phase HPLC procedure is proposed for the determination of seven flavonoids (luteolin, nepetin, hispidulin, jaceosidin, cirsimaritin, cirsilineol, and eupatorin) in vervain samples. A simple...

Inhibition of [methyl-3H]diazepam binding to rat brain membranes in vitro by dinatin and skrofulein.

Zhongguo Yao Li Xue Bao 15(5) , 385-8, (1994)

Two flavones, 4',5,7-trihydroxy-6-methoxy flavone (dinatin) and 4',5-dihydroxy-6, 7-dimethoxy flavone (skrofulein), were extracted from Artemisia herba alba L. Dinatin and skrofulein inhibited the bin...

Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography.

J. Pharm. Biomed. Anal. 48(1) , 100-4, (2008)

To control the quality of Salvia plebeia R.Br., a simple and reliable method of high-performance liquid chromatography coupled with photodiode array detector (HPLC-DAD) was developed both for fingerpr...


More Articles

Related Compounds

  • Hispidulin
  • hispidulin acetate
  • hispidulin-7-glucoside
  • hispidulin-7-O-β-glucuronide
  • Hispidulin 4'-O-β-D-glucopyranoside
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • (2-Chloro-4-fluorophenyl)(4-(2-cyclopropyl-2-hydroxyethyl)piperazin-1-yl)methanone hydrochloride
  • tert-Butyl-DL-alanine
  • (3-((4-Fluorophenyl)sulfonyl)azetidin-1-yl)(pyridin-2-yl)methanone