Telmisartan

Suppliers

Names

[ Name ]:
Telmisartan

[Synonym ]:
Kinzalmono
Micardis
4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
MFCD00929085
4'-[(1,7'-Dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]-2-biphenylcarboxylic acid
[1,1'-Biphenyl]-2-carboxylic acid, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-
Pritor
Telmisartan
EINECS 620-494-7

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
771.9±70.0 °C at 760 mmHg

[ Melting Point ]:
261-263°C

[ Molecular Formula ]:
C₃₃H₃₀N₄O₂

[ Molecular Weight ]:
514.617

[ Flash Point ]:
420.6±35.7 °C

[ Exact Mass ]:
514.236877

[ PSA ]:
72.94000

[ LogP ]:
7.73

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.667

[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid hydrochloride
Telmisartan Amide
carbon monoxide
3'-((2'-bromobiphenyl-4-yl)methyl)-1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzo[d]imidazole
4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
Telmisartan methyl ester
Acetylene
4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester

DownStream

Articles

Preventing leptin resistance by blocking angiotensin II AT1 receptors in diet-induced obese rats.

Br. J. Pharmacol. 172(3) , 857-68, (2015)

AT1 receptor blockers (ARBs) represent an approach for treating metabolic syndrome due to their potency in reducing hypertension, body weight and onset of type 2 diabetes. The mechanism underlying ARB...

Behavior of sartans (antihypertensive drugs) in wastewater treatment plants, their occurrence and risk for the aquatic environment.

Environ. Sci. Pollut. Res. Int. 21(18) , 10830-9, (2014)

Pharmaceuticals and other anthropogenic trace contaminants reach wastewaters and are often not satisfactorily eliminated in sewage treatment plants. These contaminants and/or their degradation product...

Preconcentration of indapamide from human urine using molecularly imprinted solid-phase extraction.

J. Sep. Sci. 38 , 3090-5, (2015)

A simple, sensitive, and selective molecularly imprinted solid-phase extraction and spectrophotometric method has been developed for the clean-up and preconcentration of indapamide from human urine. M...

Telmisartan-d3
TelMisartan API
Telmisartan Amide
Telmisartan sodium
Telmisartan-13C,d3
Telmisartan impurity
7-[2-(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-oxoethoxy]-4-methyl-2H-chromen-2-one
2,4,6-Trimethyl-N-(2-methylpropyl)benzenamine
N-(3-fluorobenzyl)-1H-imidazole-1-carboxamide
3,6-dichloro-N-{2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl}pyridine-2-carboxamide
2-(6-chloro-1H-indol-1-yl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
(2E)-N-[(2E)-4-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2(3H)-ylidene]-3-phenylprop-2-enamide
N-[2-(5-chloro-1H-indol-3-yl)ethyl]-2-[2-(1H-pyrrol-1-yl)-1,3-thiazol-4-yl]acetamide
2-(3-methylbutyl)-1,3-dioxo-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2,3-dihydro-1H-isoindole-5-carboxamide
4-{[(5-methoxy-1H-indol-1-yl)acetyl]amino}benzamide
N-(prop-2-en-1-yl)-2-(1H-tetrazol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

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