5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzylene}-2,4-thiazolidinedione

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Names

[ CAS No. ]:
144809-28-9

[ Name ]:
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzylene}-2,4-thiazolidinedione

[Synonym ]:
(5E)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene}-1,3-thiazolidine-2,4-dione
(5E)-5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene}-1,3-thiazolidine-2,4-dione
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (5E)-
Pioglitazone Impurity 2

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
156-159°C

[ Molecular Formula ]:
C19H18N2O3S

[ Molecular Weight ]:
354.423

[ Exact Mass ]:
354.103821

[ PSA ]:
93.59000

[ LogP ]:
2.76

[ Index of Refraction ]:
1.653

[ Storage condition ]:
-20°C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperidine
  • 2,4-Thiazolidinedione
  • 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzaldehyde
  • 4-hydroxybenzaldehyde
  • 5-ethyl-2-vinyl pyridine
  • Hydroxy Pioglitazone (M-II)
  • 5-{4-[2-chloro-2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidene dione
  • 2-Pyridinemethanol,alpha-(bromomethyl)-5-ethyl-(9CI)
  • 5-Ethyl-2-pyridineethanol
  • 2-Pyridineethanol, 5-ethyl-, 1-oxide

DownStream

  • Pioglitazone hydrochloride
  • 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

Related Compounds

  • N-(2-hydroxy-2-methyl-4-phenylbutyl)furan-2-carboxamide
  • N-(2-hydroxy-2-methyl-4-phenylbutyl)-5-methylisoxazole-3-carboxamide
  • N-(2-hydroxy-2-methyl-4-phenylbutyl)thiophene-2-carboxamide
  • N-(2-hydroxy-2-methyl-4-phenylbutyl)thiophene-3-carboxamide
  • 4-fluoro-N-(2-hydroxy-2-methyl-4-phenylbutyl)benzamide
  • N-(2-hydroxy-2-methyl-4-phenylbutyl)-2,5-dimethylbenzamide
  • N-(2-hydroxy-2-methyl-4-phenylbutyl)-4-methoxybenzamide
  • 4-chloro-N-(2-hydroxy-2-methyl-4-phenylbutyl)benzamide
  • 2-(2,5-dioxopyrrolidin-1-yl)-N-(2-hydroxy-2-methyl-4-phenylbutyl)acetamide
  • 2-(4-fluorophenoxy)-N-(2-hydroxy-2-methyl-4-phenylbutyl)acetamide
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