5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzylene}-2,4-thiazolidinedione

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Names

[ CAS No. ]:
144809-28-9

[ Name ]:
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzylene}-2,4-thiazolidinedione

[Synonym ]:
(5E)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene}-1,3-thiazolidine-2,4-dione
(5E)-5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene}-1,3-thiazolidine-2,4-dione
5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (5E)-
Pioglitazone Impurity 2

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
156-159°C

[ Molecular Formula ]:
C19H18N2O3S

[ Molecular Weight ]:
354.423

[ Exact Mass ]:
354.103821

[ PSA ]:
93.59000

[ LogP ]:
2.76

[ Index of Refraction ]:
1.653

[ Storage condition ]:
-20°C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperidine
  • 2,4-Thiazolidinedione
  • 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzaldehyde
  • 4-hydroxybenzaldehyde
  • 5-ethyl-2-vinyl pyridine
  • Hydroxy Pioglitazone (M-II)
  • 5-{4-[2-chloro-2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidene dione
  • 2-Pyridinemethanol,alpha-(bromomethyl)-5-ethyl-(9CI)
  • 5-Ethyl-2-pyridineethanol
  • 2-Pyridineethanol, 5-ethyl-, 1-oxide

DownStream

  • Pioglitazone hydrochloride
  • 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

Related Compounds

  • (2S)-2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]pentanoic acid
  • (2R,4R)-1-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]-4-hydroxypyrrolidine-2-carboxylic acid
  • 2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-(2-methylpropyl)hexanamido]acetic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-({[2-(methoxymethyl)oxolan-2-yl]methyl}carbamoyl)propanoic acid
  • 2-[(2R)-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoyl]pyrrolidin-2-yl]acetic acid
  • 2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]methyl}cyclohexane-1-carboxylic acid
  • 5-(4-benzyl-3,3-dimethylpiperazin-1-yl)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid
  • 3-[ethyl(2-methoxypropyl)carbamoyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(3-hydroxy-4-methylpyrrolidin-1-yl)-4-oxobutanoic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2,6-difluorobenzoic acid
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