Rifamycin O

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Names

[ CAS No. ]:
14487-05-9

[ Name ]:
Rifamycin O

[Synonym ]:
(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,11-trioxo-9-(4-oxo-1,3-dioxolan-2-yl)-1,2,6,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
4-o-(carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-rifamycigamma-la
2,7-(Epoxy[1,11,13]pentadecatrienoimino)naphtho[2,1-b]furan-1,6,11(2H,9H)-trione, 21-(acetyloxy)-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-9-(4-oxo-1,3-dioxolan-2-yl)-, (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-
Rifamycin O
Rifomycin O
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-Trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,29-trioxo-27-(4-oxo-1,3-dioxolan-2-yl)-8,30-dioxa-24-azatetracyclo[23.3.1.1.0]triaconta-1(28),2,4,9,19,21,25-heptaen-13-yl acetate
4-O-(Carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxorifamycin g-lactone
ctone
rifamycin-O

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
972.8±65.0 °C at 760 mmHg

[ Melting Point ]:
171ºC (dec.)

[ Molecular Formula ]:
C39H47NO14

[ Molecular Weight ]:
767.815

[ Flash Point ]:
542.2±34.3 °C

[ Exact Mass ]:
767.315308

[ PSA ]:
213.45000

[ LogP ]:
1.38

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.608

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • rifamycin B

DownStream

  • RifamycinS

Related Compounds

  • Rifamycin,25-O-deacetyl-1,4,21-trideoxy-1,4-dihydro-1,4,21-trioxo-, cyclic23,25-(1-methylethylidene acetal) (9CI)
  • Rifamycin,25-O-deacetyl-3-formyl-
  • Rifamycin, {4-O-[2-(hexahydro-1H-azepin-1-yl)-2-oxoethyl]-}
  • Rifamycin, 4-O-[2-oxo-2- (tripropylhydrazino)ethyl]-
  • Rifamycin,4-O-[2-[bis(2-methylpropyl)amino]-2-oxoethyl]- (9CI)
  • Rifamycin, 25-O-deacetyl
  • 3-(3-Chloro-5-(trifluoromethyl)phenyl)propanal
  • 1,5,9,13,17-Pentaoxacycloicosane
  • 2,5-difluoro-N-methylpyridin-3-amine
  • Allyl (5-amino-4-chloro-1,3-benzothiazol-2-yl)methyl carbonate
  • 5-phenyl-N-(2-(pyrimidin-5-yl)ethyl)isoxazole-3-carboxamide
  • N-(2-(pyrimidin-5-yl)ethyl)-3-(trifluoromethyl)benzamide
  • ethyl (2R)-2-amino-4,4,4-trifluoro-3-(trifluoromethyl)butanoate
  • 2,6-dichloro-N-[4-(2,6-difluorophenyl)-1,3-thiazol-2-yl]pyridine-3-carboxamide
  • N-(2-(pyrimidin-5-yl)ethyl)-2-(trifluoromethyl)benzamide
  • 4-oxo-N-(2-(pyrimidin-5-yl)ethyl)-4H-chromene-2-carboxamide