5-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Names

[ CAS No. ]:
144881-42-5

[ Name ]:
5-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Boiling Point ]:
440.6ºC at 760mmHg

[ Molecular Formula ]:
C14H19ClN4O

[ Molecular Weight ]:
294.78000

[ Flash Point ]:
220.3ºC

[ Exact Mass ]:
294.12500

[ PSA ]:
51.59000

[ LogP ]:
1.81660

[ Vapour Pressure ]:
5.81E-08mmHg at 25°C

[ Index of Refraction ]:
1.662

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP6742000
CHEMICAL NAME :
2-Oxazolamine, 4,5-dihydro-5-((4-(2-chlorophenyl)-1-piperazinyl)meth yl)-
CAS REGISTRY NUMBER :
144881-42-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H19-Cl-N4-O
MOLECULAR WEIGHT :
294.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
437 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 27,437,1992

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2,1-Benzisoxazole-3-carboxylic acid, 6-(hydroxymethyl)-
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide