5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Names

[ CAS No. ]:
144881-48-1

[ Name ]:
5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
462.7ºC at 760mmHg

[ Molecular Formula ]:
C16H24N4O2

[ Molecular Weight ]:
304.38700

[ Flash Point ]:
233.6ºC

[ Exact Mass ]:
304.19000

[ PSA ]:
60.82000

[ LogP ]:
1.56190

[ Vapour Pressure ]:
9.68E-09mmHg at 25°C

[ Index of Refraction ]:
1.618

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP6746500
CHEMICAL NAME :
2-Oxazolamine, 4,5-dihydro-5-((4-(4-methoxyphenyl)-3-methyl-1-pipera zinyl)methyl)-
CAS REGISTRY NUMBER :
144881-48-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H24-N4-O2
MOLECULAR WEIGHT :
304.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
524 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 27,437,1992

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(4-METHOXYPHENYL)-2-METHYLPIPERAZINE, 1:1 MIXTURE OF CONFORMERS
  • cyanamide,sodium

DownStream

Related Compounds

  • 2-Pyridinecarbonyl chloride, 4-cyano-5-(trifluoromethyl)-
  • 4-Phenyl-6-(trifluoromethyl)nicotinic acid
  • 1-(4-Ethoxyphenyl)-2-fluoroethan-1-amine
  • 5-(3,4-Dichlorophenyl)picolinonitrile
  • 3-Pyridinecarbonitrile, 5-amino-2-formyl-4-(trifluoromethoxy)-
  • 3-Pyridineacetic acid, 5-methoxy-2-phenyl-
  • 4-(4-Aminophenoxy)-n-methylbenzamide
  • 2-Pyridinecarbonitrile, 6-(2,3,4,5,6-pentafluorophenyl)-
  • 6-bromo-2-(prop-2-yn-1-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • 6-Hydroxy-5-(trifluoromethyl)nicotinaldehyde
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