5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Names

[ CAS No. ]:
144881-48-1

[ Name ]:
5-[[4-(2-ethoxyphenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
462.7ºC at 760mmHg

[ Molecular Formula ]:
C16H24N4O2

[ Molecular Weight ]:
304.38700

[ Flash Point ]:
233.6ºC

[ Exact Mass ]:
304.19000

[ PSA ]:
60.82000

[ LogP ]:
1.56190

[ Vapour Pressure ]:
9.68E-09mmHg at 25°C

[ Index of Refraction ]:
1.618

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP6746500
CHEMICAL NAME :
2-Oxazolamine, 4,5-dihydro-5-((4-(4-methoxyphenyl)-3-methyl-1-pipera zinyl)methyl)-
CAS REGISTRY NUMBER :
144881-48-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H24-N4-O2
MOLECULAR WEIGHT :
304.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
524 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 27,437,1992

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(4-METHOXYPHENYL)-2-METHYLPIPERAZINE, 1:1 MIXTURE OF CONFORMERS
  • cyanamide,sodium

DownStream

Related Compounds

  • 1,1,5,5,5-Pentafluoropentan-2-ol
  • 3-Cyclopropyl-1,1-difluoropropan-2-ol
  • 2-Methyl-2-(1,2,3,4-tetrahydroquinolin-6-yl)propanoic acid
  • Methyl 2-methyl-2-(1,2,3,4-tetrahydroquinolin-6-yl)propanoate
  • 1-(1,2,3,4-Tetrahydroquinolin-6-yl)cyclopropane-1-carboxylic acid
  • 1-(1,2,3,4-Tetrahydroquinolin-6-yl)cyclobutane-1-carboxylic acid
  • Methyl 1-(1,2,3,4-tetrahydroquinolin-6-yl)cyclobutane-1-carboxylate
  • Methyl 1-(1,2,3,4-tetrahydroquinolin-6-yl)cyclopropane-1-carboxylate
  • 3-(1,2,3,4-Tetrahydroquinolin-6-yl)oxetane-3-carboxylic acid
  • Methyl 3-(1,2,3,4-tetrahydroquinolin-6-yl)oxetane-3-carboxylate
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