5'-Chloro-2'-hydroxyacetophenone

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Names

[ CAS No. ]:
1450-74-4

[ Name ]:
5'-Chloro-2'-hydroxyacetophenone

[Synonym ]:
5-Chloro-2-hydroxyacetophenone
5'-chloro-2'- hydroxyacetophenone
Ethanone, 1- (5-chloro-2-hydroxyphenyl)-
5'-Chloro-2'-hydroxyacetophenone
EINECS 215-916-8
2-acetyl-4-chlorophenol
Acetophenone,5'-chloro-2'-hydroxy
2'-Hydroxy-5'-chloroacetophenone
1-(5-Chloro-2-hydroxyphenyl)ethanone
5′-Chloro-2′-hydroxyacetophenone
Acetophenone, 5'-chloro-2'-hydroxy-
Ethanone, 1-(5-chloro-2-hydroxyphenyl)-
MFCD00067788

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
270.9±25.0 °C at 760 mmHg

[ Melting Point ]:
54-56 °C(lit.)

[ Molecular Formula ]:
C8H7ClO2

[ Molecular Weight ]:
170.593

[ Flash Point ]:
117.6±23.2 °C

[ Exact Mass ]:
170.013458

[ PSA ]:
37.30000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-CHLOROPHENOL ACETATE
  • Ortho-Hydroxyacetophenone
  • 4-Chlorophenol
  • Acetyl chloride
  • 3-methyl-2-oxido-1,2-benzoxazol-2-ium
  • 4-chloro-6-[1-(hydroxyamino)ethylidene]cyclohexa-2,4-dien-1-one
  • 1-(5-Chloro-2-methoxyphenyl)ethanone
  • acetic acid
  • 5-Chloro-2-methoxybenzonitrile

DownStream

  • 2-(1-((4-BROMOPHENYL)IMINO)ETHYL)-4-CHLOROPHENOL
  • 1-(5-Chloro-2-hydroxyphenyl)-3-phenyl-1,3-propanedione
  • 6-Chloro-4-oxo-4H-chromene-3-carbaldehyde
  • 2-BROMO-5'-CHLORO-2'-HYDROXYACETOPHENONE
  • 6-Chlorochromanone
  • 6-chlorochromone
  • 4-chloro-2-[1-(pyridin-2-yl)-1H-pyrazol-3-yl]phenol
  • 4-chloro-2-[1-(pyridin-2-yl)-1H-pyrazol-5-yl]phenol
  • 3,5-Dichloro-2-hydroxyacetophenone
  • 6-chloro-2-(4-fluorophenyl)chromen-4-one

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

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Antivir. Chem. Chemother. 14(4) , 195-203, (2003)

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Related Compounds

  • 2-BROMO-5'-CHLORO-2'-HYDROXYACETOPHENONE
  • 3'-bromo-5'-chloro-2'-hydroxyacetophenone
  • 5'-chloro-2'-hydroxy-4'-methylacetophenone
  • 5'-CHLORO-2'-HYDROXY-4'-METHYL-3'-NITROACETOPHENONE
  • 5'-chloro-2',3'-didehydro-3',5'-dideoxythymidine
  • 5'-Chloro-2',4'-dimethoxy-2-fluoroacetanilide