ω-Agatoxin IVa trifluoroacetate salt

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Names

[ CAS No. ]:
145017-83-0

[ Name ]:
ω-Agatoxin IVa trifluoroacetate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁₇H₃₆₀N₆₈O₆₀S₁₀

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

P-type calcium channels blocked by the spider toxin omega-Aga-IVA.

Nature 355 , 827-829, (1992)

Voltage-dependent calcium channels mediate calcium entry into neurons, which is crucial for many processes in the brain including synaptic transmission, dendritic spiking, gene expression and cell dea...

P-type calcium channels in rat central and peripheral neurons.

Neuron 9 , 85-95, (1992)

The peptide toxin omega-Aga-IVA blocked P-type Ca2+ channel current in rat Purkinje neurons (KD approximately 2 nM) but had no effect on identified T-type, L-type, or N-type currents in a variety of c...

Calcium channels coupled to glutamate release identified by omega-Aga-IVA.

Science 258 , 310-313, (1992)

Presynaptic calcium channels are crucial elements of neuronal excitation-secretion coupling. In mammalian brain, they have been difficult to characterize because most presynaptic terminals are too sma...