Rizatriptan benzoate

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Names

[ Name ]:
Rizatriptan benzoate

[Synonym ]:
Rizatriptan benzoate salt
N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine monobenzoate
N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine benzoate
Rizatriptan benzoate
1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, benzoate (1:1)
N,N-Dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine benzoate (1:1)
Maxalt
MK-462 (N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
Rizatrimptan benzoate
MFCD00866224
Benzolcarbonsäure--N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamin(1:1)
N,N-diméthyl-2-[5-(1H-1,2,4-triazol-1-ylméthyl)-1H-indol-3-yl]éthanamine benzoate
Rizatriptan
N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine Benzoate

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
504.8ºC at 760mmHg

[ Melting Point ]:
178-180°C

[ Molecular Formula ]:
C₂₂H₂₅N₅O₂

[ Molecular Weight ]:
391.466

[ Flash Point ]:
259.1ºC

[ Exact Mass ]:
391.200836

[ PSA ]:
87.04000

[ LogP ]:
3.29660

[ Vapour Pressure ]:
2.58E-10mmHg at 25°C

[ Index of Refraction ]:
1.645

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P280-P308 + P313

[ Hazard Codes ]:
C,Xi

[ Risk Phrases ]:
R34:Causes burns.

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
3259

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Evolution of paediatric off-label use after new significant medicines become available for adults: a study on triptans in Finnish children 1994-2007.

Br. J. Clin. Pharmacol. 71(6) , 929-35, (2011)

• Off-label use in children is widespread. New medicines lack marketing authorization for paediatric use, even when they represent significant therapeutic advantages and are intended for treatment of ...

An approach for rapid development of nasal delivery of analgesics--identification of relevant features, in vitro screening and in vivo verification.

Int. J. Pharm. 420(1) , 43-50, (2011)

Drug delivery via the nasal route is gaining increasing interest over the last two decades as an alternative to oral or parenteral drug administration. In the current study an approach for rapid ident...

Efficacy and tolerability of rizatriptan for the treatment of acute migraine in sumatriptan non-responders.

Cephalalgia 31(7) , 786-96, (2011)

The study was carried out to assess the efficacy and tolerability of rizatriptan orally disintegrating tablet (ODT) for treating acute migraine in patients who are non-responders to sumatriptan.Many m...

[2H6]-Rizatriptan benzoate
Rizatriptan benzoate impurity G [EP]
Rizatriptan benzoate impurity H [EP]
Rizatriptan benzoate impurity F [EP]
Rizatriptan Dimer Benzoate
Rizatriptan
2-Amino-3-(3-fluoro-4-methoxyphenyl)-3-hydroxypropanoic acid
HYPOLAETIN 8-O-beta-D-GLUCURONIDE
(2S,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxochromen-8-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
N-[2-Methoxy-5-(1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]-4-(1-methylpropoxy)benzamide
2-(2,3-Dimethylphenoxy)-N-[2-methoxy-5-(1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]acetamide
(1-(1H-Imidazol-5-yl)cyclopropyl)methanamine
L-Alanyl-N-methyl-L-alaninamide
V5X6XQ6PJ4
1-Methyl-3-pyrrolidinepropanol
5-(Oxan-2-yloxy)pent-2-ynal

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