methyl (4R,5S)-3-benzyl-4-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-propan-2-yl-1,3-oxazolidine-4-carboxylate

Names

[ CAS No. ]:
145451-93-0

[ Name ]:
methyl (4R,5S)-3-benzyl-4-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-propan-2-yl-1,3-oxazolidine-4-carboxylate

Chemical & Physical Properties

[ Density]:
1.02g/cm3

[ Boiling Point ]:
445.243ºC at 760 mmHg

[ Molecular Formula ]:
C22H37NO4Si

[ Molecular Weight ]:
407.61900

[ Flash Point ]:
223.075ºC

[ Exact Mass ]:
407.24900

[ PSA ]:
48.00000

[ LogP ]:
4.37240

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.492

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • tert-Butyldimethylsilyl chloride
  • methyl (2R,4R)-3-benzyl-2-tert-butyl-4-[(1S)-1-hydroxy-2-methylpropyl]-1,3-oxazolidine-4-carboxylate
  • METHYL (2R,3S)-2-BENZYLAMINO-3-HYDROXY-2-HYDROXYMETHYL-4-METHYLPENTANOATE

DownStream

  • (3R,4S,5S,6S)-1-Aza-5-(t-butyldimethylsilyloxymethyl)-4-hydroxy-6-isopropyl-3-methyl-7-oxabicyclo[3.3.0]-octan-2-one
  • (4R,5S)-N-Benzyl-4-(t-butyldimethylsilyloxymethyl)-4-hydroxymethyl-5-isopropyloxazoladine
  • (3R,4S,5R,6S)-1-AZA-4-HYDROXY-5-HYDROXYMETHYL-6-ISOPROPYL-3-METHYL-7-OXABICYCL[3.3.0]OCTAN-2-ONE
  • (3R,4S)-(-)-1-BENZYL-3,4-PYRROLIDINDIOL