Mitiglinide (Calcium)
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Names
[ CAS No. ]:
145525-41-3
[ Name ]:
Mitiglinide (Calcium)
[Synonym ]:
Mitiglinide
Mitiglinide calcium
MFCD08458378
(aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt
[2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
Mitiglinide hemicalcium salt
Mitiglinide (Calcium)
Chemical & Physical Properties
[ Density]:
1.175
[ Boiling Point ]:
519.6ºC at 760 mmHg
[ Melting Point ]:
146-148ºC
[ Molecular Formula ]:
C19H24NO3Ca0.5
[ Molecular Weight ]:
334.44
[ Flash Point ]:
268ºC
[ PSA ]:
102.45000
[ LogP ]:
5.59450
[ Vapour Pressure ]:
1.27E-11mmHg at 25°C
[ Storage condition ]:
room temp
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
36
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2942000000
Customs
[ HS Code ]: 2942000000
Articles
Diabetes Obes. Metab. 14(2) , 187-9, (2012)
This study was performed to examine the efficacy and safety of mitiglinide in type 2 diabetes patients (T2DM). Enrolled patients had received treatment with diet and exercise in the previous 3 months ...
Eur. J. Drug Metab. Pharmacokinet. 37(1) , 9-15, (2012)
Nateglinide and mitiglinide are immediate short-acting insulinotropic agents. Both are administered preprandially to control postprandial hyperglycemia. Glinide drugs are characterized by immediate on...
Diabetes Obes. Metab. 14(2) , 130-8, (2012)
Insulin secretagogues promote insulin release by binding to sulfonylurea receptors on pancreatic β-cells (SUR1). However, these drugs also bind to receptor isoforms on cardiac myocytes (SUR2A) and vas...