1,3,4-Thiadiazole,2-methyl-5-phenyl-

Suppliers

Names

[ CAS No. ]:
1456-72-0

[ Name ]:
1,3,4-Thiadiazole,2-methyl-5-phenyl-

[Synonym ]:
Methyl-phenyl-[1,3,4]thiadiazol
5-Methyl-2-phenyl-1,3,4-thiodiazol
1,3,4-Thiadiazole,2-methyl-5-phenyl
2-methyl-5-phenyl-[1,3,4]thiadiazole
methyl-phenyl-[1,3,4]thiadiazole
2-Metil-5-fenil-1,3,4-tiadiazolo [Italian]
2-Phenyl-5-methyl-1,3,4-thiodiazol
L 1539

Chemical & Physical Properties

[ Density]:
1.199g/cm3

[ Boiling Point ]:
309.6ºC at 760mmHg

[ Molecular Formula ]:
C9H8N2S

[ Molecular Weight ]:
176.23800

[ Flash Point ]:
139.6ºC

[ Exact Mass ]:
176.04100

[ PSA ]:
54.02000

[ LogP ]:
2.51350

[ Vapour Pressure ]:
0.00115mmHg at 25°C

[ Index of Refraction ]:
1.599

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI4320000
CHEMICAL NAME :
1,3,4-Thiadiazole, 2-methyl-5-phenyl-
CAS REGISTRY NUMBER :
1456-72-0
BEILSTEIN REFERENCE NO. :
0127290
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H8-N2-S
MOLECULAR WEIGHT :
176.25
WISWESSER LINE NOTATION :
T5NN DSJ C1 ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Cardiac - other changes Lungs, Thorax, or Respiration - other changes
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,187,1958

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzoic acid,2-acetylhydrazide
  • N-acetimidoyl-N'-thiobenzoylhydrazine
  • Benzothiohydrazide
  • Thioacetamide
  • [5-hydroxy-3-methyl-5-(trifluoromethyl)-4,5-dihydro-1Н-pyrazol-1-yl](phenyl)thioketone
  • 2,2-dimethyl-5-phenyl-3H-1,3,4-thiadiazole
  • S-(Thiobenzoyl)thioglycolic acid
  • Phenyllithium
  • 1-chloro-1,4-diphenyl-2,3-diazabutadiene

DownStream

  • (5-phenyl-1,3,4-thiadiazol-2-yl)methanamine
  • 5-phenyl-1,3,4-thiadiazole-2-carbaldehyde
  • 2-phenyl-1,3,4-thiadiazole

Related Compounds

  • 6-methyl-3-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
  • 1,3,4-Thiadiazole,2-methyl-5-nitro-
  • methyl-(2-nitro-phenyl)-[1,3,4]thiadiazole
  • 2-(4-chlorophenyl)-5-methyl-1,3,4-thiadiazole
  • 1,3,4-Oxadiazole, 2-methyl-5-phenyl-
  • 1,3,4-Thiadiazole,2-[(2-methyl-5-nitro-1H-imidazol-1-yl)methyl]-