CGP 52411

Suppliers

Names

[ CAS No. ]:
145915-58-8

[ Name ]:
CGP 52411

[Synonym ]:
5,6-bis-phenylamino-isoindole-1,3-dione
DAPH-1
4,5-dianilinophthalimide
DAPH
5,6-bis-phenylamino-isoindole-1,3-dione,DAPH

Chemical & Physical Properties

[ Density]:
1.374 g/cm3

[ Melting Point ]:
199-202℃

[ Molecular Formula ]:
C20H15N3O2

[ Molecular Weight ]:
329.35200

[ Exact Mass ]:
329.11600

[ PSA ]:
70.23000

[ LogP ]:
4.53220

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • dimethyl 4,5-dianilinobenzene-1,2-dicarboxylate
  • 4,5-Dichlorophthalic acid
  • 4,5-dichlorophthalic acid dimethyl ester

DownStream

Articles

A chemical-genetic interaction map of small molecules using high-throughput imaging in cancer cells.

Mol. Syst. Biol. 11 , 846, (2015)

Small molecules often affect multiple targets, elicit off-target effects, and induce genotype-specific responses. Chemical genetics, the mapping of the genotype dependence of a small molecule's effect...

Umbelliferone and daphnetin ameliorate carbon tetrachloride-induced hepatotoxicity in rats via nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1 expression

Environ. Toxicol. Pharmacol. 38(2) , 531-41, (2014)

• This study demonstrates the hepatoprotective effect of umbelliferone and daphnetin. • Both coumarins ameliorate CCl4-induced oxidative stress and hepatotoxicity. • This effect is mediated via the nu...

Gene activation and protein expression following ischaemic stroke: strategies towards neuroprotection.

J. Cell. Mol. Med. 9 , 85-102, (2005)

Current understanding of the patho-physiological events that follow acute ischaemic stroke suggests that treatment regimens could be improved by manipulation of gene transcription and protein activati...


More Articles

Related Compounds

  • CGP 25454A
  • CGP 15425
  • CGP 39551
  • CGP 65015
  • CGP 57698
  • CGP-20712
  • 5-(3-chlorobenzyl)-8-fluoro-3-(3-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
  • 8-fluoro-3-(3-methoxybenzyl)-5-(3-methylbenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
  • 3-(2-chlorobenzyl)-5-(2-chloro-6-fluorobenzyl)-8-fluoro-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one
  • 2-(5-Propyl-1,3,4-oxadiazol-2-yl)phenylboronic acid
  • 4-(1-Benzyl-1h-pyrazol-4-yl)phenylboronic acid
  • 2-(5-Isopropyl-1,3,4-oxadiazol-2-yl)phenylboronic acid
  • 5-(4-chlorobenzyl)-3-(2-methoxybenzyl)-8-methyl-3H-pyrimido[5,4-b]indol-4(5H)-one
  • 5-(3-chlorobenzyl)-3-(2-methoxybenzyl)-8-methyl-3H-pyrimido[5,4-b]indol-4(5H)-one
  • 5-(2-chloro-4-fluorobenzyl)-3-(2-methoxybenzyl)-8-methyl-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one
  • 5-(3-chlorobenzyl)-3-(3,4-dimethoxyphenethyl)-8-methyl-3H-pyrimido[5,4-b]indol-4(5H)-one
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