2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline

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Names

[ CAS No. ]:
146578-99-6

[ Name ]:
2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline

[Synonym ]:
2-Cyclopropyl-3-[(diphenylphosphoryl)methyl]-4-(4-fluorophenyl)quinoline
Quinoline, 2-cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-
2-cyclopropyl-3-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)quinoline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
627.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H25FNOP

[ Molecular Weight ]:
477.509

[ Flash Point ]:
333.2±31.5 °C

[ Exact Mass ]:
477.165771

[ PSA ]:
39.77000

[ LogP ]:
6.24

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.676

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl diphenylphosphinite
  • 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
  • Ethyldiphenylphosphinate
  • 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

DownStream

  • (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

Related Compounds

  • 1-(Iodomethyl)-2,8-dioxaspiro[4.5]decane
  • Tert-butyl 4-(6-bromopicolinamido)piperidine-1-carboxylate
  • O-[2-(4-chlorothiophen-2-yl)propan-2-yl]hydroxylamine
  • 3-Hydroxy-3-(4-methoxy-3-nitrophenyl)propanenitrile
  • 3-(2,4,5-Trifluorophenyl)propane-1-sulfonyl fluoride
  • {1-[(2,4-Difluoro-6-methoxyphenyl)methyl]cyclopropyl}methanamine
  • 1-(3-Bromopyridin-4-yl)-3,3-difluorocyclobutan-1-amine
  • 3-(1,2,3,4-Tetrahydronaphthalen-1-yl)-1,2-oxazole-5-carboxylic acid
  • 4-(1,2,3,4-Tetrahydronaphthalen-1-yl)but-3-en-2-one
  • 2-(2-Cyclopropylphenyl)ethanimidamide
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