2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline

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Names

[ CAS No. ]:
146578-99-6

[ Name ]:
2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline

[Synonym ]:
2-Cyclopropyl-3-[(diphenylphosphoryl)methyl]-4-(4-fluorophenyl)quinoline
Quinoline, 2-cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-
2-cyclopropyl-3-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)quinoline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
627.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H25FNOP

[ Molecular Weight ]:
477.509

[ Flash Point ]:
333.2±31.5 °C

[ Exact Mass ]:
477.165771

[ PSA ]:
39.77000

[ LogP ]:
6.24

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.676

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl diphenylphosphinite
  • 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
  • Ethyldiphenylphosphinate
  • 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

DownStream

  • (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

Related Compounds

  • 7-Bromo-2-chloro-3-(methoxymethyl)quinoline
  • 1,4-Dimethyl-3-(1-methylcyclopentyl)-1H-pyrazol-5-amine
  • 1-(7-Bromo-4-chloro-2-quinolinyl)ethanone
  • 1-[7-Bromo-3-(methoxymethyl)-2-quinolinyl]ethanone
  • 1-{7-methyl-5H,6H,7H,8H-imidazo[1,2-a]pyridin-2-yl}methanamine
  • 2-(3-Chloro-4-fluorophenyl)-3-methylbutanoic acid
  • Acetamide, N-methyl-2-[[1-(4,5,6,7-tetrahydrobenzo[b]thien-2-yl)ethyl]amino]-
  • 2-(Thian-2-yl)pyrimidine-4-carboxylic acid
  • 3-((4-Fluorophenyl)sulfonyl)-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-amine
  • 4,5,6,7-Tetrahydrobenzo[c]isothiazol-3-amine
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