3-[[3-bromo-2-[2-(trifluoromethylsulfonylamino)phenyl]-1-benzofuran-5-yl]methyl]-5-cyclopropyl-2-ethylimidazole-4-carboxamide

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Names

[ CAS No. ]:
146623-69-0

[ Name ]:
3-[[3-bromo-2-[2-(trifluoromethylsulfonylamino)phenyl]-1-benzofuran-5-yl]methyl]-5-cyclopropyl-2-ethylimidazole-4-carboxamide

[Synonym ]:
Saprisartan
Saprisartan potassium

Chemical & Physical Properties

[ Density]:
1.7g/cm3

[ Boiling Point ]:
707.3ºC at 760mmHg

[ Molecular Formula ]:
C25H22BrF3N4O4S

[ Molecular Weight ]:
611.43100

[ Flash Point ]:
381.5ºC

[ Exact Mass ]:
610.05000

[ PSA ]:
128.60000

[ LogP ]:
7.76140

[ Vapour Pressure ]:
7.48E-20mmHg at 25°C

[ Index of Refraction ]:
1.686

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N,N-Carbonyldiimidazole
  • 1-[[3-bromo-2-[2-[[(trifluoromethyl)sulfonyl]amino]phenyl]-5-benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylic acid
  • Ethyl 3-cyclopropyl-3-oxopropanoate
  • 5-Methylbenzofuran
  • Methyl 2-bromobenzoate
  • 2-(3-bromo-5-methyl-2-benzofuranyl)benzoic acid
  • ethyl 4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxylate

DownStream

Related Compounds

  • 3-[(2S)-oxiran-2-yl]-2-(piperidin-1-yl)pyridine
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-I(2),4-dioxo-3-quinolinepropanoic acid
  • Ethyl 2-fluoro-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienoate
  • I(2)-Amino-1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole-3-propanoic acid
  • (2S)-2-(3,5-Dihydroxyphenyl)-2,3-dihydro-5,6,7-trihydroxy-4H-1-benzopyran-4-one
  • (1S)-3-amino-1-(3-chloro-5-fluorophenyl)propan-1-ol
  • 1,1-Dimethylethyl 5-amino-2-[4-(trifluoromethyl)phenyl]-1-piperidinecarboxylate
  • 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-(1-oxo-3-phenyl-2-propen-1-yl)-
  • Phosphonic acid, (3,4-dihydro-2-methyl-5-phenyl-2H-pyrrol-3-yl)-, diethyl ester
  • 3-Ethyl 5-(2-carboxyethenyl)-2-methyl-1-(phenylmethyl)-1H-pyrrole-3-carboxylate
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