3-Amino-4(3H)-quinazolinone

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Names

[ CAS No. ]:
14663-46-8

[ Name ]:
3-Amino-4(3H)-quinazolinone

[Synonym ]:
3-amino-3H-quinazolin-4-one
3-amino-3,4-dihydroquinazolin-4-one
3-Amino-3H-chinazolin-4-on
3-amino-4-oxo-3,4-dihydroquinazoline
MFCD01038386
3-Amino-4(3H)-quinazolinone

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Boiling Point ]:
348.9ºC at 760 mmHg

[ Melting Point ]:
209-213ºC(lit.)

[ Molecular Formula ]:
C8H7N3O

[ Molecular Weight ]:
161.16100

[ Flash Point ]:
164.8ºC

[ Exact Mass ]:
161.05900

[ PSA ]:
60.91000

[ LogP ]:
0.69150

[ Vapour Pressure ]:
4.87E-05mmHg at 25°C

[ Index of Refraction ]:
1.702

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA2330000
CHEMICAL NAME :
4(3H)-Quinazolinone, 3-amino-
CAS REGISTRY NUMBER :
14663-46-8
BEILSTEIN REFERENCE NO. :
0131407
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H7-N3-O
MOLECULAR WEIGHT :
161.18
WISWESSER LINE NOTATION :
T66 BVN ENJ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,202,1967

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Quinazolinone
  • METHYL 2-[(ETHOXYMETHYLENE)AMINO]BENZOATE
  • Triethyl orthoformate
  • 2-aminobenzhydrazide
  • Methyl 2-aminobenzoate
  • 2,1-Benzisoxazol-3(1H)-one
  • Formic Acid
  • ethyl 5-(4-oxoquinazolin-3-yl)-1-phenylpyrazole-4-carboxylate

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-AMINO-2-ETHYL-4(3H)-QUINAZOLINONE
  • 3-Amino-2-(trifluoromethyl)-4(3H)-quinazolinone
  • 3-amino-2-ethoxycarbonylmetylenethio-4(3H)-quinazolinone
  • 3-AMINO-6,7-DIMETHOXY-4(3H)-QUINAZOLINONE
  • 3-Amino-2-n-propyl-4(3H)-quinazolinone
  • 2-methyl-3-(phenylmethylene)-amino-4(3H)quinazolinone
  • tert-butyl N-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]carbamate
  • 4-{[(Tert-butoxy)carbonyl]amino}-2-hydroxy-3,5-diiodobenzoic acid
  • tert-butyl N-(5-bromo-2-fluoro-4-hydroxyphenyl)carbamate
  • tert-butyl N-[1-(2-hydroxyethyl)-1H,4H,5H,6H,7H,8H-cyclohepta[c]pyrazol-4-yl]carbamate
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{[3-(4-methyl-4H-1,2,4-triazol-3-yl)propyl]carbamoyl}propanoic acid
  • 3-(4-Methylphenyl)-5-(trifluoromethyl)-[1,2]oxazolo[5,4-b]pyridine
  • 1-Amino-3-(5-nitrothiophen-2-yl)propan-2-ol
  • 2-{1-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]cyclobutyl}acetic acid
  • (2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-3-methylpentanoic acid
  • 4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]-2-hydroxybutanoic acid
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