Cyanamide,N,N-dimethyl-

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Names

[ CAS No. ]:
1467-79-4

[ Name ]:
Cyanamide,N,N-dimethyl-

[Synonym ]:
DIMETHYLCYANAMIDE
EINECS 215-991-7

Chemical & Physical Properties

[ Density]:
0.867 g/mL at 25 °C(lit.)

[ Boiling Point ]:
161-163 °C(lit.)

[ Melting Point ]:
-41 °C

[ Molecular Formula ]:
C₃H₆N₂

[ Molecular Weight ]:
70.09310

[ Flash Point ]:
137 °F

[ Exact Mass ]:
70.05310

[ PSA ]:
27.03000

[ LogP ]:
0.02908

[ Vapour Pressure ]:
2.06mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.41(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GS6475000

CHEMICAL NAME :: Cyanamide, dimethyl-

CAS REGISTRY NUMBER :: 1467-79-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H6-N2

MOLECULAR WEIGHT :: 70.11

WISWESSER LINE NOTATION :: NCN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 146 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/m3

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 73 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2800 mg/m3

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 146 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(11),23,1975

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4863,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R23/24/25;R36/37/38

[ Safety Phrases ]:
36/37/39-45

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
GS6475000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Cyanogen bromide
Dimethylamine
2-dimethylaminoacetamide
dimethylaminomethylideneurea
1,2-bis(dimethylamino)-1,2-dichloroethene
POTASSIUM CYANIDE
1,1-DIMETHYLUREA
Chloromethane
Cyanamide

DownStream

4H-1,2,4-Triazole-3,4,5-triamine
1,1-DIMETHYLUREA
1,1-dimethyl-2-selenourea
triethylsilylformonitrile
Succinimide
1,4-Benzodioxin
2-N,2-N,4-N,4-N-tetramethyl-1,3,5-triazine-2,4,6-triamine
2,4-Diamino-6-dimethylamino-1,3,5-triazine
1,3-Dimethylurea
Tetramethylguanidine

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

Cyanamide, N,N-dibutyl-
(E)-N,N-dimethyl-5-phenyl-pent-4-en-1-amine
Ethanamine, N,N-dimethyl-2-[[1,2,3,4-tetrahydro-1-(2-quinoxalinyl)-6-isoquinolinyl]oxy]- (9CI)
Hexanethioamide,N,N-dimethyl-
(R)-N,N-dimethyl-3-(2-nitro-4-sulfamoylphenylamino)-4-phenylsulfanylbutyramide
Ethanethioamide,N,N-dimethyl-2-(methylphenylamino)-
3-[(2S)-3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-1-methyl-1H-pyrazole-4-carboxylic acid
2-{N-[2-(dimethylamino)ethyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido}acetic acid
4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,4,4-trimethylpentanamido]butanoic acid
(2R)-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methylphenyl]formamido}pentanoic acid
1-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-enamido]ethyl}-1H-imidazole-4-carboxylic acid
(2R)-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-fluorophenyl]formamido}pentanoic acid
2-({[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]formamido}methyl)-2-methylbutanoic acid
4-{[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]formamido}-2-methylbutanoic acid
2-{3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]cyclopentyl}acetic acid
2-{3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]cyclopentyl}acetic acid

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