PF 06409577

Suppliers

Names

[ CAS No. ]:
1467057-23-3

[ Name ]:
PF 06409577

[Synonym ]:
6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid
PF-06409577

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆ClNO₃

[ Molecular Weight ]:
341.78800

[ Exact Mass ]:
341.08200

[ PSA ]:
73.32000

[ LogP ]:
4.55800

[ Storage condition ]:
-20℃

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. Cameron KO et al

J. Med. Chem. 59(17) , 8068-81, (2016)

PF-06471553
PF-05085727
PF-03463275
PF-06815189
PF-06869206
PF 945863
Tert-butyl ((1-(6-chloropyrimidin-4-yl)pyrrolidin-3-yl)methyl)carbamate
tert-butyl ((1-(5-nitro-1H-benzo[d]imidazol-2-yl)pyrrolidin-3-yl)methyl)carbamate
5-bromo-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)nicotinamide
N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)-1H-benzo[d][1,2,3]triazole-5-carboxamide
3-phenyl-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)benzo[c]isoxazole-5-carboxamide
2-(benzo[d]isoxazol-3-yl)-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)acetamide
4-(pyrrolidin-1-ylsulfonyl)-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)benzamide
Tert-butyl ((1-(3-aminoquinoxalin-2-yl)pyrrolidin-3-yl)methyl)carbamate
2-(pyridin-3-yl)-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)acetamide
2-(thiophen-3-yl)-N-((5-(thiophen-3-yl)pyridin-3-yl)methyl)acetamide

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