4-(aziridin-1-yl)-6-chloropyrimidine

Names

[ CAS No. ]:
14673-04-2

[ Name ]:
4-(aziridin-1-yl)-6-chloropyrimidine

[Synonym ]:
Pyrimidine,4-(1-aziridinyl)-6-chloro
4-Ethyleneimino-6-chloropyrimidine
4-(1-Aziridinyl)-6-chloropyrimidine
4-aziridin-1-yl-6-chloro-pyrimidine

Chemical & Physical Properties

[ Density]:
1.455g/cm3

[ Boiling Point ]:
303.4ºC at 760mmHg

[ Molecular Formula ]:
C6H6ClN3

[ Molecular Weight ]:
155.58500

[ Flash Point ]:
137.3ºC

[ Exact Mass ]:
155.02500

[ PSA ]:
28.79000

[ LogP ]:
1.01500

[ Vapour Pressure ]:
0.000933mmHg at 25°C

[ Index of Refraction ]:
1.635

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV6803000
CHEMICAL NAME :
Pyrimidine, 4-(1-aziridinyl)-6-chloro-
CAS REGISTRY NUMBER :
14673-04-2
BEILSTEIN REFERENCE NO. :
0908490
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H6-Cl-N3
MOLECULAR WEIGHT :
155.60
WISWESSER LINE NOTATION :
T6N CNJ DG F- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
96 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
245 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970

Related Compounds

  • 4-(aziridin-1-yl)-6-methyl-5-nitropyrimidin-2-amine
  • 4-(aziridin-1-yl)-6-chloro-N-(4-chlorophenyl)pyrimidin-2-amine
  • 4-aziridin-1-yl-6-chloro-2-methylsulfanyl-pyrimidine
  • 4-(aziridin-1-yl)-6-phenylpyrimidin-2-amine
  • 4-(aziridin-1-yl)-6-chloro-2-(4-methoxyphenyl)pyrimidine
  • 4-(aziridin-1-yl)-6-chloro-2-naphthalen-2-ylpyrimidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • rac-(2R,3R)-1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoyl]-2-methylpiperidine-3-carboxylic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-fluoro-2-(4-methyl-1H-imidazol-1-yl)benzaldehyde
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • rac-1-methyl-3-[(1R,2R,4S)-7-oxabicyclo[2.2.1]heptan-2-yl]-1H-pyrazol-5-amine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde