2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite

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Names

[ CAS No. ]:
146954-75-8

[ Name ]:
2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite

[Synonym ]:
3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-deoxy-2'-fluoro-
2'-F-dUPhosphoramidite
2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite

Chemical & Physical Properties

[ Molecular Formula ]:
C39H46FN4O8P

[ Molecular Weight ]:
748.777

[ Exact Mass ]:
748.303711

[ PSA ]:
150.86000

[ LogP ]:
8.04

MSDS

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Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

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Precursor & DownStream

Precursor

  • 5'-DMT-2'-F-dU
  • 4,4'-Dimethoxytrityl chloride

DownStream

Related Compounds

  • 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite
  • 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
  • 5'-O-DMT-2'-F-2'-arabinofuranosyl-deoxyuridine 3'-CE phosphoramidite
  • 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite
  • 2’-Fluoro-2’-deoxy-N6,N6-dimethylarabinoadenosine
  • 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine