nafcillin
Suppliers
Names
[ CAS No. ]:
147-52-4
[ Name ]:
nafcillin
[Synonym ]:
Propizepina
6-(2-dimethylamino-propyl)-6,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-5-one
6-(2-Ethoxy-naphth-1-yl-formamino)penicillansaeure
nafcillinum [INN_la]
(2S,5R,6R)-6-({[2-(ethyloxy)naphthalen-1-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Propizepinum
(2-ethoxy-naphthalen-1-yl)-penicillin
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
[2S-(2a,5a,6b)]-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
Naftopen
Nallpen
Propizepinum [INN-Latin]
6-(2-Ethoxy-1-naphthamido)penicillin
Propizepina [INN-Spanish]
Vagran 50 Kapseln
Propizepine
(2S,5R,6R)-6-[(2-Ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
714.1±60.0 °C at 760 mmHg
[ Molecular Formula ]:
C21H22N2O5S
[ Molecular Weight ]:
414.475
[ Flash Point ]:
385.7±32.9 °C
[ Exact Mass ]:
414.124939
[ PSA ]:
121.24000
[ LogP ]:
3.52
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.686
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI0120000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3- dimethyl-7-oxo-
- CAS REGISTRY NUMBER :
- 147-52-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H22-N2-O5-S
- MOLECULAR WEIGHT :
- 414.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 1050 mg/kg/1W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - interstitial nephritis
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 225,178,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3659 No. of Facilities: 199 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 11979 (estimated) No. of Female Employees: 9552 (estimated)