4-Methyl-5-hydroxymethyluracil

Names

[ CAS No. ]:
147-61-5

[ Name ]:
4-Methyl-5-hydroxymethyluracil

[Synonym ]:
5-hydroxymethyl-6-methyl-1H-pyrimidine-2,4-dione
5-Hydroxymethyl-4-methyluracil
Pentoksil
MFCD00023156
5-hydroxymethyl-6-methylpyrimidine-2,4-dione
4-Methyl-5-oxymethyluracil
4-Methyl-5-hydroxymethyluracil
Pentoxyuracil
PENTOXYL
5-Hydroxymethyl-6-methyluracil
EINECS 205-694-0
5-Hydroxymethyl-6-methyl-1H-pyrimidin-2,4-dion

Chemical & Physical Properties

[ Density]:
1.308g/cm3

[ Molecular Formula ]:
C6H8N2O3

[ Molecular Weight ]:
156.13900

[ Exact Mass ]:
156.05300

[ PSA ]:
85.95000

[ Index of Refraction ]:
1.514

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YR0515000
CHEMICAL NAME :
Uracil, 5-(hydroxymethyl)-6-methyl-
CAS REGISTRY NUMBER :
147-61-5
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H8-N2-O3
MOLECULAR WEIGHT :
156.16
WISWESSER LINE NOTATION :
T6MVMVJ E1Q F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
500 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
AAGEAA Arkhiv Anatomii, Gistologii i Embriologii. Archives of Anatomy, Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-101, 1916-91. Discontinued Volume(issue)/page/year: 65(11),19,1973

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Methyluracil
  • Formaldehyde
  • CHEMBRDG-BB 4009840
  • 6-methyl-5-(((1-phenyl-1H-tetrazol-5-yl)thio)methyl)pyrimidine-2,4(1H,3H)-dione

DownStream

  • 5-BENZYLOXYMETHYL-6-METHYLURACIL
  • 5-Pyrimidinecarboxaldehyde,1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-
  • 6-Methyluracil
  • Formaldehyde
  • 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine
  • acetic acid
  • Urea
  • CHEMBRDG-BB 4009840
  • 3-[5-(methoxymethyl)-2,4-dioxo-1H-pyrimidin-6-yl]propyl acetate
  • 1,3-dibenzyl-6-methyl-5-(phenylmethoxymethyl)pyrimidine-2,4-dione

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%