2-(Trifluoromethyl)pyridin-4-amine

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Names

[ CAS No. ]:
147149-98-2

[ Name ]:
2-(Trifluoromethyl)pyridin-4-amine

[Synonym ]:
2-(Trifluoromethyl)pyridin-4-amine 4-Amino-2-trifluoromethylpyridine
2-(Trifluoromethyl)pyridin-4-amine
4-Amino-2-(trifluoromethyl)pyridine
4-Pyridinamine, 2-(trifluoromethyl)-
2-(Trifluoromethyl)-4-pyridinamine
2-trifluoromethyl-4-amino pyridine
4-Amino-2-trifluoromethylpyridine
Enasidenib Intermediate 4

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
230.7±40.0 °C at 760 mmHg

[ Melting Point ]:
58-62°C

[ Molecular Formula ]:
C6H5F3N2

[ Molecular Weight ]:
162.113

[ Flash Point ]:
93.3±27.3 °C

[ Exact Mass ]:
162.040482

[ PSA ]:
38.91000

[ LogP ]:
2.11

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.479

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
T,Xi

[ Risk Phrases ]:
25-36-43

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
2811

[ Packaging Group ]:
Ⅲ

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Nitro-2-(trifluoromethyl)pyridine 1-oxide
  • 4-Nitro-2-(trifluoromethyl)pyridine
  • 2-(Trifluoromethyl)pyridine 1-oxide
  • (Z)-1,1,1-trifluoro-6-methoxyhex-5-en-3-yn-2-one
  • 2-(Trifluoromethyl)pyridine
  • 2-Chloro-6-(trifluoromethyl)pyridine

DownStream

  • phenyl N-[2-(trifluoromethyl)pyridin-4-yl]carbamate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-Iodo-2-(trifluoromethyl)pyridin-4-amine
  • 5-nitro-2-(trifluoromethyl)pyridin-4-amine
  • 3-Bromo-2-(trifluoromethyl)pyridin-4-amine
  • 5-chloro-2-(trifluoromethyl)pyridin-4-amine
  • 5-Fluoro-2-(trifluoromethyl)pyridin-4-amine
  • N-Phenyl-2-(trifluoromethyl)pyridin-4-amine
  • (3-Methylisothiazole-4-carbonyl)glycine
  • N-Cyclopentyl-1-(pyrido[2,3-b]pyrazin-7-yl)piperidine-3-carboxamide
  • 3-(Difluoromethyl)cyclobutane-1-sulfonyl chloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-(Bromomethyl)-4-(4,4,4-trifluorobutoxy)oxane
  • Dicyclohexylamine 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate
  • [2-(Propan-2-yloxy)pyrimidin-4-yl]methanol
  • 4-Bromo-5-ethyl-N'-((5-fluorothiophen-2-yl)methylene)thiophene-2-carbohydrazide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Chloro-3-(difluoromethyl)-5-methyl-4-nitropyridine