I-bu-rG Phosphoramidite

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Names

[ CAS No. ]:
147201-04-5

[ Name ]:
I-bu-rG Phosphoramidite

[Synonym ]:
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
ibu-rGPhosphoramidite
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-
CEPA-rG
I-bu-rG Phosphoramidite

Chemical & Physical Properties

[ Molecular Formula ]:
C50H68N7O9PSi

[ Molecular Weight ]:
970.176

[ Exact Mass ]:
969.458557

[ PSA ]:
197.90000

[ LogP ]:
12.44

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Cyanoethyltetraisopropylphosphorodiamidite
  • 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
  • Diisopropylamine

DownStream