10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-
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Names
[ CAS No. ]:
14759-04-7
[ Name ]:
10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-
[Synonym ]:
KS 33
Oxyridazine
Oxiridazinum
Chemical & Physical Properties
[ Density]:
1.137g/cm3
[ Boiling Point ]:
503.5ºC at 760mmHg
[ Molecular Formula ]:
C21H26N2OS
[ Molecular Weight ]:
354.50900
[ Flash Point ]:
258.3ºC
[ Exact Mass ]:
354.17700
[ PSA ]:
41.01000
[ LogP ]:
5.17520
[ Vapour Pressure ]:
2.89E-10mmHg at 25°C
[ Index of Refraction ]:
1.597
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SP0875000
- CHEMICAL NAME :
- Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-
- CAS REGISTRY NUMBER :
- 14759-04-7
- BEILSTEIN REFERENCE NO. :
- 6118065
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H26-N2-O-S
- MOLECULAR WEIGHT :
- 354.55
- WISWESSER LINE NOTATION :
- T C666 BN ISJ EO1 B2- BT6NTJ A1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,27,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 760 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIGZAY Niigata Igakkai Zasshi. Niigata Medical Journal. (Niigata Igakkai, 1, Asahi-machi, Niigata 951, Japan) V.60- 1946- Volume(issue)/page/year: 82,607,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 516 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969
Safety Information
[ HS Code ]:
2934300000
Customs
[ HS Code ]: 2934300000
[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%