Acetamide,N,N'-[1,4-phenylenebis(methylene)]bis[2,2-dichloro-N-ethyl- (9CI)
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Names
[ CAS No. ]:
1477-20-9
[ Name ]:
Acetamide,N,N'-[1,4-phenylenebis(methylene)]bis[2,2-dichloro-N-ethyl- (9CI)
[Synonym ]:
1,4-Bis-<N-dichloracetyl-N-ethylaminomethyl>-benzol
WIN 13,099
Chemical & Physical Properties
[ Density]:
1.339g/cm3
[ Boiling Point ]:
512.2ºC at 760mmHg
[ Molecular Formula ]:
C16H20Cl4N2O2
[ Molecular Weight ]:
414.15400
[ Flash Point ]:
263.6ºC
[ Exact Mass ]:
412.02800
[ PSA ]:
40.62000
[ LogP ]:
3.99100
[ Vapour Pressure ]:
1.32E-10mmHg at 25°C
[ Index of Refraction ]:
1.56
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC7732000
- CHEMICAL NAME :
- Acetamide, N,N'-(p-phenylenedimethylene)bis(2,2-dichloro-N-ethyl -
- CAS REGISTRY NUMBER :
- 1477-20-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C16-H20-Cl4-N2-O2
- MOLECULAR WEIGHT :
- 414.18
- WISWESSER LINE NOTATION :
- GYGVN2&1R D1N2&VYGG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 600 mg/kg
- SEX/DURATION :
- male 42 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- male 70 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2250 mg/kg
- SEX/DURATION :
- male 18 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5250 mg/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 20700 mg/kg
- SEX/DURATION :
- male 23 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 36 gm/kg
- SEX/DURATION :
- male 24 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
MUTATION DATA
- TEST SYSTEM :
- Human
- DOSE/DURATION :
- 3800 mg/kg/19W
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,1,1961
Safety Information
[ HS Code ]:
2924299090
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%