4-Methylbenzo[d]thiazol-2-amine

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Names

[ CAS No. ]:
1477-42-5

[ Name ]:
4-Methylbenzo[d]thiazol-2-amine

[Synonym ]:
MFCD00005793
4-Methylbenzo[d]thiazol-2-amine
2-Amino-4-methyl benzothiazole
EINECS 216-028-3
2-Benzothiazolamine, 4-methyl-
2-Amino-4-Methylbenzothiazole
4-Methyl-1,3-benzothiazol-2-amine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
322.0±35.0 °C at 760 mmHg

[ Melting Point ]:
137-139 °C(lit.)

[ Molecular Formula ]:
C8H8N2S

[ Molecular Weight ]:
164.227

[ Flash Point ]:
148.6±25.9 °C

[ Exact Mass ]:
164.040817

[ PSA ]:
67.15000

[ LogP ]:
2.35

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.726

[ Water Solubility ]:
<0.1 g/100 mL at 24 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL2275000
CHEMICAL NAME :
Benzothiazole, 2-amino-4-methyl-
CAS REGISTRY NUMBER :
1477-42-5
BEILSTEIN REFERENCE NO. :
0129346
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C8-H8-N2-S
MOLECULAR WEIGHT :
164.24
WISWESSER LINE NOTATION :
T56 BN DSJ CZ H1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
697 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,486,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
54 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,486,1952

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S28-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DL2275000

[ HS Code ]:
2934200090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Methylcyclohexanone
  • 1-(2-Methylphenyl)thiourea
  • o-Toluidine
  • Potassium thiocyanate
  • o-Toluidine HCl
  • 4-Methyl-2-mercaptobenzothiazole
  • Sulfuryl chloride
  • Chlorobenzene

DownStream

  • 2-CHLORO-4-METHYLBENZOTHIAZOLE
  • Tricyclazole
  • Acetamide, N-(4-methyl-2-benzothiazolyl)- (9CI)
  • N-Phenylrhodanine
  • 2,2'-hydrazobis(4-methylbenzothiazole) hydrobromide
  • 1,2-bis(6-methylbenzo[d]thiazol-2-yl)hydrazine hydrobromide
  • 1,2-bis(5-chlorobenzo[d]thiazol-2-yl)hydrazine hydrobromide
  • 1,2-bis(4-chlorobenzo[d]thiazol-2-yl)hydrazine hydrobromide
  • 2-chloro-N-(4-methyl-1,3-benzothiazol-2-yl)acetamide

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Ultra-high performance liquid chromatography tandem high-resolution mass spectrometry study of tricyclazole photodegradation products in water.

Environ. Sci. Pollut. Res. Int. 22 , 8288-95, (2015)

This paper reports the study of the photodegradation reactions that tricyclazole can naturally undergo, under the action of sunlight, in aqueous solutions of standard tricyclazole and of the commercia...

SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITIES OF SOME TRANSITION METAL COMPLEXES CONTAINING 2-ACETONAPHTHONE. Mishra AP and Mishra DP.

Int. J. Pharm. Biol. Sci. 2(3) , 430-39, (2011)

Experimental and theoretical surface enhanced Raman scattering study of 2-amino-4-methylbenzothiazole adsorbed on colloidal silver particles.

J. Phys. Chem. B 109(47) , 22536-44, (2005)

The adsorption of 2-amino-4-methylbenzothiazole (2-AMBT) on colloidal silver particles has been investigated by a surface enhanced Raman scattering (SERS) study. The SERS spectra of the 2-AMBT molecul...


More Articles

Related Compounds

  • 4-methylbenzo[d]thiazol-2-amine
  • 5-bromo-4-methylbenzo[d]thiazol-2-amine
  • 5-CHLORO-4-METHYLBENZO[D]THIAZOL-2-AMINE
  • N-(3-(1H-Imidazol-1-yl)propyl)-5-chloro-4-methylbenzo[d]thiazol-2-amine
  • 4-METHYLBENZO[D]THIAZOL-2(3H)-ONE
  • 4-Bromo-5-methylbenzo[d]thiazol-2-amine