Ethyl succinyl chloride

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Names

[ Name ]:
Ethyl succinyl chloride

[Synonym ]:
3-ethoxycarbonyl-propionyl chloride
Ethyl succinyl chloride(ESC)
ETHYL 4-CHLORO-4-OXOBUTYRATE
ETHYLSS-BENZOYLACRYLATE
ethyl 3-(chlorocarbonyl)propanoate
Ethyl succinyl chloride
Butanoic acid, 4-chloro-4-oxo-, ethyl ester
3-carboethoxy-propionyl chloride
Monoethyl succinyl chloride
Ethyl 4-chloro-4-oxobutanoate
Ethyl succinoyl chloride
3-Carbethoxypropionyl chloride
3-chlorocarbonyl-propionic acid ethyl ester
Ethyl siccinyl chloride
MFCD00000751
Propionic acid, 3-(chloroformyl)-, ethyl ester
Succinic Acid Monoethyl Ester Chloride
EINECS 238-855-9

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
207.8±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₉ClO₃

[ Molecular Weight ]:
164.587

[ Flash Point ]:
84.4±0.0 °C

[ Exact Mass ]:
164.024017

[ PSA ]:
43.37000

[ LogP ]:
1.26

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.436

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45-S24/25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Ethoxy-4-oxobutanoic acid
Succinic anhydride
Ethanol
Diethyl succinate
Monoethyl fumarate

DownStream

4-Oxooctanoic acid ethyl ester
ethyl 4-(4-fluorophenyl)-4-oxobutanoate
4-(4-Methoxyphenyl)-4-oxobutanoic acid
Ethyl 4-Oxohexanoate
ethyl 4-oxo-4-thiophen-3-ylbutanoate
4-NAPHTHALEN-1-YL-4-OXO-BUTYRIC ACID
2-Naphthalenebutanoicacid, g-oxo-
ethyl 5-chloro-4-oxopentanoate
Ethyl 5-bromo-4-oxopentanoate
ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis, characterization and biological evaluation of succinate prodrugs of curcuminoids for colon cancer treatment.

Molecules 16(2) , 1888-900, (2011)

A novel series of succinyl derivatives of three curcuminoids were synthesized as potential prodrugs. Symmetrical (curcumin and bisdesmethoxycurcumin) and unsymmetrical (desmethoxycurcumin) curcuminoid...

Enantioselective Strecker-type reaction promoted by polymer-supported bifunctional catalyst. Nogami H, et al.

Tetrahedron Lett. 42(2) , 279-83, (2001)

Surface plasmon resonance detection of endocrine disruptors using immunoprobes based on self-assembled monolayers. Gobi KV, et al.

Sens. Actuators B Chem. 108(1) , 784-90, (2005)

Ethyl succinyl chloride
Methyl succinyl chloride
Methyl succinyl chloride
monoethyl succinyl chloride
ethyl-succinyl azide
benzyl-succinyl chloride
1-(6-Chloro-2-cyclopropylpyrimidin-4-yl)azepane
6-chloro-N,2-dicyclopropylpyrimidin-4-amine
3-(1-Amino-2,2-difluoroethyl)phenol
4-Chloro-2-cyclopropyl-6-(pyrrolidin-1-yl)pyrimidine
6-chloro-2-cyclopropyl-N-isobutylpyrimidin-4-amine
6-chloro-2-cyclopropyl-N-(1-methoxypropan-2-yl)pyrimidin-4-amine
4-bromo-3-chloro-N-methylbenzamide
1-[(4-Bromo-3-fluorophenyl)methyl]piperidin-4-amine
4-(6-Chloro-2-cyclopropylpyrimidin-4-yl)morpholine
Benzeneacetic acid, 4-bromo-I+/--[(cyclopropylmethyl)amino]-3-fluoro-

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